Multidisciplinary Cardiovascular Research Centre

Multidisciplinary Cardiovascular Research Centre

Cardiovascular discovery and therapeutics

Commercialisation Opportunities

Internal Centres


External Collaborations by PI

Dr Ramzi Ajjan

Dr Ramzi Ajjan has collaborations with;

Dr. Angiolillo, USA: Effects of antiplatelet treatment on clot structure

Prof. R Boger, Germany: The role of SDMA and AMDA in diabetes

Dr. K Hess, Germany: The complement system in diabetes: human and animal studies.

Dr. V Shroeder, Switzerland: The role of MASP-1 in thrombosis potential in Diabetes.

Dr. A Undas, Poland: Differences in clotting parameters of diabetes subjects with and without established CVD.

Prof S. Heller, Sheffield: The effects of hypoglycaemia on thrombosis potential.

Dr. R Storey, Sheffield: Mechanisms for the reduced clinical efficacy of aspirin in diabetes

Prof K Naseem, Hull: Interactions between platelets and fibrinogen/FXIII

Prof. Atkin, Hull: Clotting parameters in insulin resistance states

Dr. M Strachan/Dr. J Price, Edinburgh: Fibrin clot structure/fibrinolysis in older individuals with type 2 diabetes

Dr. K Kos, Exeter: Obesity, GLP-1 analogues and thrombosis potential

Dr. K Owen, Oxford: cardiovascular risk in maturity onset diabetes of the young (MODY)

Professor David Beech

Dr Martin Main and Dr Simon Barry (AstraZeneca, Alderley Edge, UK)

Dr Michael Saunders (arGEN-X, Belgium)

Professor K Muraki (Aichigakuin University, Nagoya, Japan)

Professor Enrico Stefani (UCLA, USA)

Dr Sarah Calaghan

Dr Sarah Calaghan has collaborations with;

Professor Robert Harvey, University of Nevada Reno, US.  ‘ Measurement of cAMP with high temporal and spatial resolution using genetically-encoded FRET based cAMP biosensors’,
http://www.medicine.nevada.edu/dept/pharmacology/faculty/harvey.html

Dr Will Fuller, University of Dundee.  ‘Quantitative caveolar proteomics using iTRAQ’,
http://www.dundee.ac.uk/medschool/staff/will-fuller/

Professor John Colyer

Professor John Colyer has collaborations with;

Rebecca Sitsapesan (University of Bristol), ‘Functional consequences of RYR2 phosphorylation’

Rob Beynon (University of Liverpool), ‘Quantitative proteomics’

Dek Woolfson (University of Bristol), ‘Synthetic biology: engineering bioresponsive polymers’

Richard Jones (University of Chicago), ‘Quantitative systems biology’

Edwin Moore (University of British Columbia, Canada), ‘Decoding signal transduction mechanisms in the heart’

Dr John Greenwood

2011-2014 NIHR (EME). Gershlick, McCann, Abrams, Goodall, Greenwood, Blackman. Randomized Controlled Trial Comparing Intracoronary Administration of Adenosine or Sodium Nitroprusside to Control for Attenuation of Microvascular Obstruction during Primary Percutaneous Coronary Intervention)

2011-2013 NIHR (EME). McCann, Gershlick, Greenwood, Blackman, Curzon, Dalby, Flather. Complete Versus Lesion-only PRimary PCI pilot Cardiac MRI substudy (CVLPRI-t-CMR).

Professor Eileen Ingham

Professor Eileen Ingham has collaborations with;

Tissue Regenix www.tissueregenix.com/.  Commercial development of xenogeneic cardiovascular biological scaffolds.

NHS Blood and Transplant Tissue Services www.nhsbt.nhs.uk/tissueservices/aboutus/ourteam/. Clinical translation of allogeneic cardiovascular biological scaffolds.

Francisco da Costa, Department Of Cardiovascular Surgery of Santa Casa de Curitiba, PUCPR, Curitiba, Paraná, Brazil.  Large animal models and clinical studies

Dr Sven Plein

Dr Sven Plein has collaborations with;

Institute for Biomedical Engineering, an institution of the Swiss Federal Institute of Technology (ETH Zurich) and the University of Zurich,
http://www.biomed.ee.ethz.ch

Rayne Institute, Division of Imaging, King’s College London, http://www.kcl.ac.uk/schools/medicine/research/imaging

Dr Vas Ponnambalam

Dr Vas Ponnambalam has collaborations with;

Prof. Ian Zachary at University College London, http://www.ucl.ac.uk/medicine/people/show.php?personid=12505

Professor Tony Monaco at the University of Oxford, http://www.well.ox.ac.uk/monaco-2

Professor John Findlay at the University of Maynooth, Eire, http://biology.nuim.ie/staff/JFMembraneProteins.shtml

Professor Mario Alberghina at the University of Catania, Sicily, Italy, http://www3.unict.it/aos/web_staff.htm

Dr Eleanor Scott

Dr Eleanor Scott has collaborations with;

Prof Derk-Jan Dijk – Professor of Sleep and Physiology, Director Surrey Sleep Research Centre, Guildford, Surrey, http://www2.surrey.ac.uk/fhms/research/centres/ssrc/People/dijk_dj/
Collaborating on research investigating the effects of sleep and sleep interventions on cardiovascular and diabetes disease outcomes.

Dr Simon Archer – Reader in Chronobiology, University of Surrey, Guildford, Surrey
http://www2.surrey.ac.uk/biochemistry/People/simon_archer/
Collaborating on research investigating the role of circadian clock polymorphisms in cardio-metabolic disease

Dr Denise Robertson – Lecturer in Nutritional Physiology, University of Surrey, Guildford, Surrey
http://www2.surrey.ac.uk/nutrition/People/robertson_denise/
Collaborating on research investigating the effects of sleep interventions and clock polymorphisms on energy metabolism in diabetes

Dr Steve Lockley – Assistant Professor of Medicine, Harvard Medical School, Boston, USA
http://sleep.med.harvard.edu/people/faculty/163/

Collaborating on research investigating diurnal variation in fibrin clot structure/function

Dr Nelson Chong – Lecturer in Molecular Cardiology, Cardiovascular Sciences, University of Leicester, Leicester.
http://www2.le.ac.uk/departments/cardiovascular-sciences/people/chong
.
Collaborating on research investigating the effect of tissue specific clock mutations on cardiac function.

Professor John Trinick

Professor John Trinick has collaborations with;

Dr Howard White, Eastern Virginia Medical School, Norfolk, Virginia. Dr White specialises in contractile protein reactions mechanisms, especially their study by fast kinetic methods.
http://www.evms.edu/evms-dept.-of-physiological-sciences/howard-d-white-phd-professor.html


Dr John Kendrick-Jones, MRC Laboratory of Molecular Biology, Cambridge. Dr Kendrick-Jones studies cellular myosins, especially myosin VI, which walks along actin filaments in the opposite direction to all other myosins studied.
http://www2.mrc-lmb.cam.ac.uk/research/structuralstudies/johnkendrickjones

Dr Samantha Harris, University of California at Davis. Dr Harris studies the biochemistry and physiology of C-protein (MyBP-C), which is a major protein in heart with unknown function but is a major cause of heart disease.
http://www.npb.ucdavis.edu/labs/harris/index.htm

Professor Ed White

Professor Ed White has collaborations with;

Dr. Holly Shiels, University of Manchester. Vertebrate cardiac muscle. http://www.ls.manchester.ac.uk/research/researchgroups/channelsandtransporters/people/index.aspx?PersonID=1488

Dr. Olivier Cazorla, Universite de Montpellier and INSERM -1046, France. Cardiac sarcomeric protein regulation.
http://www.univ-montp1.fr/recherche/unites_de_recherche/physiologie_medecine_experimentale_du_c_ur_et_des_muscles_inserm_u1046/equipes_teams/equipe_n_2/team_2


Dr. David Saint, University of Adelaide, Australia. Cardiac electrophysiology.
http://health.adelaide.edu.au/school_medsci/research/physiology/arrhymias/

External Collaborations by Institution

  • Aichigahuin University, Nagoya, Japan
  • arGEN-X, Belgium
  • Astrazeneca
  • Department Of Cardiovascular Surgery of Santa Casa de Curitiba, Brazil
  • University of British Columbia, Canada
  • University of Montpellier
  • Eastern Virgina Medical School
  • University of California
  • University of Nevada
  • Harvard Medical School
  • University of Catania
  • University of Oxford
  • MRC Laboratory of Molecular Biology, Cambridge
  • University College London
  • University of Surrey
  • NHS Blood and Transplant Tissue Services
  • University of Chicago
  • University of Zurich
  • Rayne Institute, King's College London
  • University of Dundee
  • Surrey Sleep Research Centre
  • University of Leicester
  • Tissue Regenix
  • University of California, Los Angeles
  • University of Liverpool
  • University of Adelaide
  • University of Manchester
  • University of Bristol
  • University of Monmouth