Cardio Metabolic Research at Leeds

Biomedical Imaging

 

Atherothrombosis and diabetes

This group focuses on the development and clinical translation of innovative biomedical imaging methods. The group is multidisciplinary in nature and includes computational biologists, medical physicists and clinicians. Innovations by the group include: depth-resolved optical imaging of cardiac electrical activity; advanced cardiovascular MRI, development of quantitative methods for analysis of imaging data and large scale clinical imaging studies.

With funding from the Medical Research Council and the British Heart Foundation totalling >£10m we are currently building a new facility for integrated high-field MRI, optical imaging, CT and PET/CT in a purpose built facility and a large National Centre for Hyperpolarised MRI in collaboration with the University of York. These new facilities will support major new translational cardiovascular and other imaging programmes from 2016.

 

Investigators

 

David Buckley

Professor David Buckley

I work on quantitative magnetic resonance imaging (MRI) with a focus on tracer kinetic analysis of data acquired using dynamic contrast-enhanced MRI.

Staff webpage

Erica Dall'Armellina

Information to follow...

Steve Evans

Steve Evans

My research interests are lipid membranes, micro and nanobubbles, self-assembled monolayers and nanowires and nanoparticles.

Staff webpage

John Greenwood

John Greenwood

My research is focused on the diagnosis and treatment of patients with coronary heart disease. In particular, large multi-centre clinical trials of Cardiovascular Magnetic Resonance (CMR) and Percutaneous Coronary Intervention (PCI).

Staff webpage

Arun Holden

Arun Holden

Computational electrophysiology of mammalian cardiac and smooth muscle cells, tissue and organs, based on electrophysiological data from animal experiments and clinical recordings, structural data from in vivo and ex vivo magnetic resonance imaging and architectural data from diffusion tensor MRI. Main interests are re-entrant cardiac arrhythmia in the adult, and foetal and neonatal cardiac electrophysiology.

Staff webpage

Azhar Maqbool

Azhar Maqbool

My research focuses on the role of matrix proteins in cardiac remodelling following injury and in heart failure - including their utility as markers for sites of remodelling in vivo using MRI and as plasma biomarkers for cardiac disease.

Staff webpage

James Oliver

James Oliver

I am an adult congenital cardiologist with a research interest in vascular function of patients with repaired coarctation of the aorta.

Staff webpage

Michelle Peckham

Michelle Peckham

We work on molecular motors, the cytoskeleton and muscle differentiation to understand how myosins contribute to skeletal and heart muscle contraction. We are developing and using super-resolution microscopy.

Staff webpage

Sven Plein

Picture

My research is focused on the development, validation and clinical translation of cardiovascular imaging methods, in particular magnetic resonance imaging. My group performs mechanistic and diagnostic studies in a range of conditions including heart failure and ischaemic heart disease.

Staff webpage

Jurgen Schneider

Jurgen Schneider

Development of fast cardiac MRI techniques at ultra-high fields.

Staff webpage

Steven Sourbron

Steven Sourbron

My research is in the use of quantitative and functional magnetic resonance imaging to characterize tissue function or metabolic activity. Clinically these data may be used to improve diagnosis, to plan interventions or therapy, or serve as biomarkers to evaluate the response to therapy.

Staff webpage

Peter Swoboda

Peter Swoboda

My research is focused on the use of cardiovascular magnetic resonance (CMR) to detect subclinical changes in cardiac structure in function. I have particular interests in studying patients with type 2 diabetes, heart muscle disease and highly trained athletes.

Harry Tsoumpas
Harry Tsoumpas

The aim of his current research is the development of novel approaches for the reconstruction of PET images with high quality, resolution, precision and accuracy at lower amounts of radioactivity or faster acquisitions.

Staff webpage

What's Happening

18 January 2018: Bridging the gap between molecules and millimetres: In vivo assessment of myocardial microstructure and function using diffusion tensor CMR ... more

08 February 2018:  ... more

15 February 2018: MCRC Seminar ... more

Athena Swan