Richard Cubbon
Clinical Lecturer in Cardiology
Cardiovascular and Diabetes Research
Qualifications: MBChB, MRCP, PhD
Email: R.Cubbon@leeds.ac.uk
Telephone: 0113 343 7230
Research Area
The impact of insulin resistance on vascular function and repair
Details
Recent Projects
Publications
Recent
Rajwani A; Ezzat V; Smith J; Yuldasheva NY; Duncan ER; Gage M; Cubbon RM; Kahn MB; Imrie H; Abbas A; Viswambharan H; Aziz A; Sukumar P; Vidal-Puig A; Sethi JK; Xuan S; Shah AM; Grant PJ; Porter KE; Kearney MT; Wheatcroft SB (2012) Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis. DIABETES, 61 , pp. 915-924.
Rakobowchuk M; Harris E; Taylor A; Baliga V; Cubbon RM; Rossiter HB; Birch KM (2012) Heavy and moderate interval exercise training alters low-flow-mediated constriction but does not increase circulating progenitor cells in healthy humans. EXPERIMENTAL PHYSIOLOGY, 97 , pp. 375-385.
Selected
Cubbon RM; Gale CP; Kearney LC; Schechter CB; Brooksby WP; Nolan J; Fox KAA; Rajwani A; Baig W; Groves D; Barlow P; Fisher AC; Batin PD; Kahn MB; Zaman AG; Shah AM; Byrne JA; Lindsay SJ; Sapsford RJ; Wheatcroft SB; Witte KK; Kearney MT (2011) Changing Characteristics and Mode of Death Associated With Chronic Heart Failure Caused by Left Ventricular Systolic Dysfunction A Study Across Therapeutic Eras. CIRCULATION-HEART FAILURE, 4 .
Li J; Cubbon RM; Wilson LA; Amer MS; McKeown L; Hou B; Majeed Y; Tumova S; Seymour VAL; Taylor H; Stacey M; O'Regan D; Foster R; Porter KE; Kearney MT; Beech DJ (2011) Orai1 and CRAC Channel Dependence of VEGF-Activated Ca2+ Entry and Endothelial Tube Formation. CIRCULATION RESEARCH, 108 , pp. 1190-U131.
Kahn MB; Yuldasheva NY; Cubbon RM; Smith J; Rashid ST; Viswambharan H; Imrie H; Abbas A; Rajwani A; Aziz A; Baliga V; Sukumar P; Gage M; Kearney MT; Wheatcroft SB (2011) Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration. DIABETES, 60 , pp. 1295-1303.
Cubbon RM; Murgatroyd SR; Ferguson C; Bowen TS; Rakobowchuk M; Baliga V; Cannon D; Rajwani A; Abbas A; Kahn M; Birch KM; Porter KE; Wheatcroft SB; Rossiter HB; Kearney MT (2010) Human Exercise-Induced Circulating Progenitor Cell Mobilization Is Nitric Oxide-Dependent and Is Blunted in South Asian Men. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30 , pp. 878-U626.
All
Rajwani A; Ezzat V; Smith J; Yuldasheva NY; Duncan ER; Gage M; Cubbon RM; Kahn MB; Imrie H; Abbas A; Viswambharan H; Aziz A; Sukumar P; Vidal-Puig A; Sethi JK; Xuan S; Shah AM; Grant PJ; Porter KE; Kearney MT; Wheatcroft SB (2012) Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis. DIABETES, 61 , pp. 915-924.
Rakobowchuk M; Harris E; Taylor A; Baliga V; Cubbon RM; Rossiter HB; Birch KM (2012) Heavy and moderate interval exercise training alters low-flow-mediated constriction but does not increase circulating progenitor cells in healthy humans. EXPERIMENTAL PHYSIOLOGY, 97 , pp. 375-385.
Cubbon RM; Ali N; Sengupta A; Kearney MT (2012) Insulin- and growth factor-resistance impairs vascular regeneration in diabetes mellitus. Current Vascular Pharmacology, 10 (3), pp. 271-284.
Rakobowchuk M; Harris E; Taylor A; Baliga V; Cubbon RM; Rossiter HB; Birch KM (2012) Heavy and moderate interval exercise training alters low-flow-mediated constriction but does not increase circulating progenitor cells in healthy humans. Experimental Physiology, 97 (3), pp. 375-385.
Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) (2011) The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis.. Eur Heart J, .
Abbas A; Imrie H; Viswambharan H; Sukumar P; Rajwani A; Cubbon RM; Gage M; Smith J; Galloway S; Yuldeshava N; Kahn M; Xuan S; Grant PJ; Channon KM; Beech DJ; Wheatcroft SB; Kearney MT (2011) The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium. DIABETES, 60 , pp. 2169-2178.
Cubbon RM; Gale CP; Kearney LC; Schechter CB; Brooksby WP; Nolan J; Fox KAA; Rajwani A; Baig W; Groves D; Barlow P; Fisher AC; Batin PD; Kahn MB; Zaman AG; Shah AM; Byrne JA; Lindsay SJ; Sapsford RJ; Wheatcroft SB; Witte KK; Kearney MT (2011) Changing Characteristics and Mode of Death Associated With Chronic Heart Failure Caused by Left Ventricular Systolic Dysfunction A Study Across Therapeutic Eras. CIRCULATION-HEART FAILURE, 4 .
Li J; Cubbon RM; Wilson LA; Amer MS; McKeown L; Hou B; Majeed Y; Tumova S; Seymour VAL; Taylor H; Stacey M; O'Regan D; Foster R; Porter KE; Kearney MT; Beech DJ (2011) Orai1 and CRAC Channel Dependence of VEGF-Activated Ca2+ Entry and Endothelial Tube Formation. CIRCULATION RESEARCH, 108 , pp. 1190-U131.
Kahn MB; Yuldasheva NY; Cubbon RM; Smith J; Rashid ST; Viswambharan H; Imrie H; Abbas A; Rajwani A; Aziz A; Baliga V; Sukumar P; Gage M; Kearney MT; Wheatcroft SB (2011) Insulin Resistance Impairs Circulating Angiogenic Progenitor Cell Function and Delays Endothelial Regeneration. DIABETES, 60 , pp. 1295-1303.
Kahn M; Cubbon R; Mercer B; Gherardi G; Wheatcroft A; Somers K; Liu A; Blaxill J; McLenachan J; Sivananthan M; Blackman D; Greenwood J; Wheatcroft S (2010) Impact Of Diabetes on Survival after Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction. CIRCULATION, 122 .
Cubbon RM; Murgatroyd SR; Ferguson C; Bowen TS; Rakobowchuk M; Baliga V; Cannon D; Rajwani A; Abbas A; Kahn M; Birch KM; Porter KE; Wheatcroft SB; Rossiter HB; Kearney MT (2010) Human Exercise-Induced Circulating Progenitor Cell Mobilization Is Nitric Oxide-Dependent and Is Blunted in South Asian Men. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 30 , pp. 878-U626.
Imrie H; Abbas A; Viswambharan H; Rajwani A; Cubbon RM; Gage M; Kahn M; Ezzat VA; Duncan ER; Grant PJ; Ajjan R; Wheatcroft SB; Kearney MT (2009) Vascular Insulin-Like Growth Factor-I Resistance and Diet-Induced Obesity. ENDOCRINOLOGY, 150 , pp. 4575-4582.
Cubbon RM; Kahn MB; Wheatcroft SB (2009) Effects of insulin resistance on endothelial progenitor cells and vascular repair. CLINICAL SCIENCE, 117 , pp. 173-190.
Cubbon RM; Witte KKA (2009) Cardiac resynchronisation therapy for chronic heart failure and conduction delay. BRITISH MEDICAL JOURNAL, 338 .
Cubbon RM; Witte KKA (2009) Cardiac resynchronisation therapy for chronic heart failure. BMJ (Online), 338 (7702), pp. 1064-1069.
Cubbon RM; Abbas A; Wheatcroft SB; Kilcullen N; Das R; Morrell C; Barth JH; Kearney MT; Hall AS; Investigators EMMACE2 (2008) Diabetes Mellitus and Mortality after Acute Coronary Syndrome as a First or Recurrent Cardiovascular Event. PLOS ONE, 3 .
Cubbon RM; Gale CP; Rajwani A; Abbas A; Morrell C; Das R; Barth JH; Grant PJ; Kearney MT; Hall AS (2008) Aspirin and Mortality in Patients With Diabetes Sustaining Acute Coronary Syndrome. DIABETES CARE, 31 , pp. 363-365.
Cubbon R; Kahn M; Kearney MT (2008) Secondary prevention of cardiovascular disease in type 2 diabetes and prediabetes: a cardiologist's perspective. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 62 , pp. 287-299.
Cubbon RM; Kahn M; Rajwani A; Gale CP; Kearney MT (2008) Echocardiography in the investigation of cardiomyopathy. Ultrasound, 16 (2), pp. 73-79.
Cubbon RM; Gale CP; Grant PJ; Hall AS; Kearney MT (2007) Lower rates of heart failure and death in acute coronary syndromes. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 298 , pp. 969-969.
Cubbon RM; Kearney MT (2007) Acute metabolic derangement and the heart. British Journal of Diabetes and Vascular Disease, 7 (5), pp. 218-222.
Cubbon RM; Rajwani A; Wheatcroft SB (2007) The impact of insulin resistance on endothelial function, progenitor cells and repair. Diabetes and Vascular Disease Research, 4 (2), pp. 103-111.
Cubbon RM; Rajwani A; Abbas A; Gale CP; Hall AS; Kearney MT (2007) Mortality of patients with diabetes mellitus and acute myocardial infarction. Cardiology Review, 24 (10), pp. 22-26.
Adlam D; Cubbon RM; Skehan D (2004) Implantation of an epicardial dual chamber ICD following unsuccessful percutaneous extraction of a failed ventricular shocking electrode. PACE - Pacing and Clinical Electrophysiology, 27 (5), pp. 686-687.