La Corte ALC; Carter AM; Rice GI; Duan QL; Rouleau GA; Adam A; Grant PJ; Hooper NM (2011) A Functional XPNPEP2 Promoter Haplotype Leads to Reduced Plasma Aminopeptidase P and Increased Risk of ACE Inhibitor-Induced Angioedema. HUMAN MUTATION, 32 , pp. 1326-1331.

Standeven KF; Hess K; Carter AM; Rice GI; Cordell PA; Balmforth AJ; Lu B; Scott DJ; Turner AJ; Hooper NM; Grant PJ (2011) Neprilysin, obesity and the metabolic syndrome. INTERNATIONAL JOURNAL OF OBESITY, 35 , pp. 1031-1040.

Abbas A; Imrie H; Viswambharan H; Sukumar P; Rajwani A; Cubbon RM; Gage M; Smith J; Galloway S; Yuldeshava N; Kahn M; Xuan S; Grant PJ; Channon KM; Beech DJ; Wheatcroft SB; Kearney MT (2011) The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium. DIABETES, 60 , pp. 2169-2178.

Hess K; Schroeder V; Alzahrani S; Mathai M; Howell G; Smith K; Carter AM; Marx N; Grant PJ; Ajjan R (2011) A novel mechanism for hypofibrinolysis in diabetes: the role of complement C3. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9 , pp. 140-140.

de Willige SU; Miedzak M; Carter AM; Lisman T; Rosendaal FR; Grant PJ; Philippou H; Ariens RAS (2011) Proteolytic and genetic variation of the alpha-2-antiplasmin C-terminus in myocardial infarction. BLOOD, 117 , pp. 6694-6701.

Bevan S; Meidtner K; Lorenz M; Sitzer M; Grant PJ; Markus HS (2011) Adiponectin Level as a Consequence of Genetic Variation, but Not Leptin Level or Leptin Adiponectin Ratio, Is a Risk Factor for Carotid Intima-Media Thickness. STROKE, 42 , pp. 1510-1514.

Hess K; Grant PJ (2011) Inflammation and thrombosis in diabetes. THROMBOSIS AND HAEMOSTASIS, 105 , pp. S43-S54.

Smith NL; Huffman JE; Strachan DP; Huang J; Dehghan A; Trompet S; Lopez LM; Shin S; Baumert J; Vitart V; Bis JC; Wild SH; Rumley A; Yang Q; Uitterlinden AG; Stott DJ; Davies G; Carter AM; Thorand B; Polasek O; McKnight B; Campbell H; Rudnicka AR; Chen M; Buckley BM; Harris SE; Peters A; Pulanic D; Lumley T; de Craen AJM; Liewald DC; Gieger C; Campbell S; Ford I; Gow AJ; Luciano M; Porteous DJ; Guo X; Sattar N; Tenesa A; Cushman M; Slagboom PE; Visscher PM; Spector TD; Illig T; Rudan I; Bovill EG; Wright AF; McArdle WL; Tofler G; Hofman A; Westendorp RGJ; Starr JM; Grant PJ; Karakas M; Hastie ND; Psaty BM; Wilson JF; Lowe GDO; O'Donnell CJ; Witteman JCM; Jukema JW; Deary IJ; Soranzo N; Koenig W; Hayward C (2011) Genetic Predictors of Fibrin D-Dimer Levels in Healthy Adults. CIRCULATION, 123 , pp. 1864-+.

Ajjan RA; Grant PJ (2011) The Role of Antiplatelets in Hypertension and Diabetes Mellitus. JOURNAL OF CLINICAL HYPERTENSION, 13 , pp. 305-313.

Smith KA; Adamson PJ; Pease RJ; Brown JM; Balmforth AJ; Cordell PA; Ariens RAS; Philippou H; Grant PJ (2011) Interactions between factor XIII and the alpha C region of fibrinogen. BLOOD, 117 , pp. 3460-3468.

Schroeder V; Carter AM; Dunne J; Mansfield MW; Grant PJ (2010) Proinflammatory and hypofibrinolytic phenotype in healthy first-degree relatives of patients with Type 2 diabetes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 8 , pp. 2080-2082.

Lucking AJ; Visvanathan A; Philippou H; Fraser S; Grant PJ; Connolly TM; Gardell SJ; Feuerstein GZ; Fox KAA; Booth NA; Newby DE (2010) Effect of the small molecule plasminogen activator inhibitor-1 (PAI-1) inhibitor, PAI-749, in clinical models of fibrinolysis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 8 , pp. 1333-1339.

Williams H; Pease RJ; Newell LM; Cordell PA; Graham RM; Kearney MT; Jackson CL; Grant PJ (2010) Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse. ATHEROSCLEROSIS, 210 , pp. 94-99.

Cordell PA; Kile BT; Standeven KF; Josefsson EC; Pease RJ; Grant PJ (2010) Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion. BLOOD, 115 , pp. 2674-2681.

Schulze F; Carter AM; Schwedhelm E; Ajjan R; Maas R; von Holten R; Atzler D; Grant PJ; Boeger RH (2010) Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke. ATHEROSCLEROSIS, 208 , pp. 518-523.

Imrie H; Abbas A; Viswambharan H; Rajwani A; Cubbon RM; Gage M; Kahn M; Ezzat VA; Duncan ER; Grant PJ; Ajjan R; Wheatcroft SB; Kearney MT (2009) Vascular Insulin-Like Growth Factor-I Resistance and Diet-Induced Obesity. ENDOCRINOLOGY, 150 , pp. 4575-4582.

Standeven KF; de Willige SU; Carter AM; Grant PJ (2009) Heritability of Clot Formation. SEMINARS IN THROMBOSIS AND HEMOSTASIS, 35 , pp. 458-467.

Ajjan RA; Standeven KF; Khanbhai M; Phoenix F; Gersh KC; Weisel JW; Kearney MT; Ariens RAS; Grant PJ (2009) Effects of Aspirin on Clot Structure and Fibrinolysis Using a Novel In Vitro Cellular System. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 29 , pp. 712-U196.

Williams FMK; Carter AM; Kato B; Falchi M; Bathum L; Surdulescu G; Kyvik KO; Palotie A; Spector TD; Grant PJ; Investigators E (2009) Identification of Quantitative Trait Loci for Fibrin Clot Phenotypes The EuroCLOT Study. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 29 , pp. 600-U302.

Bhastin N; Parry DJ; Scott DJA; Ariens RAS; West RM (2009) Regarding "Altered fibrin clot structure and function in individuals with intermittent claudication". JOURNAL OF VASCULAR SURGERY, 49 , pp. 1088-1089.

Carter AM; Prasad UK; Grant PJ (2009) Complement C3 and C-reactive protein in male survivors of myocardial infarction. ATHEROSCLEROSIS, 203 , pp. 538-543.

Abou-Saleh RH; Connell SD; Harrand R; Ajjan RA; Mosesson MW; Smith DAM; Grant PJ; Ariens RAS (2009) Nanoscale Probing Reveals that Reduced Stiffness of Clots from Fibrinogen Lacking 42 N-Terminal B beta-Chain Residues Is Due to the Formation of Abnormal Oligomers. BIOPHYSICAL JOURNAL, 96 , pp. 2415-2427.

La Corte AIC; Carter AM; Turner AJ; Grant PJ; Hooper NM (2008) The bradykinin-degrading aminopeptidase P is increased in women taking the oral contraceptive pill. JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 9 , pp. 221-225.

Weaver RE; Donnelly D; Wabitsch M; Grant PJ; Balmforth AJ (2008) Functional expression of glucose-dependent insulinotropic polypeptide receptors is coupled to differentiation in a human adipocyte model. INTERNATIONAL JOURNAL OF OBESITY, 32 , pp. 1705-1711.

Ajjan RA; Grant PJ (2008) The cardiovascular safety of rosiglitazone. EXPERT OPINION ON DRUG SAFETY, 7 , pp. 367-376.

Hudson BI; Carter AM; Harja E; Kalea AZ; Arriero M; Yang H; Grant PJ; Schmidt AM (2008) Identification, classification, and expression of RAGE gene splice variants. FASEB JOURNAL, 22 , pp. 1572-1580.

Scott EM; Carter AM; Grant PJ (2008) Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man. INTERNATIONAL JOURNAL OF OBESITY, 32 , pp. 658-662.

Ajjan R; Storey RF; Grant PJ (2008) Aspirin resistance and diabetes mellitus. DIABETOLOGIA, 51 , pp. 385-390.

Cubbon RM; Gale CP; Rajwani A; Abbas A; Morrell C; Das R; Barth JH; Grant PJ; Kearney MT; Hall AS (2008) Aspirin and Mortality in Patients With Diabetes Sustaining Acute Coronary Syndrome. DIABETES CARE, 31 , pp. 363-365.

Scott EM; Carter AM; Grant PJ (2008) Diabetes and cardiovascular disease: Related disorders created by disturbances in the endogenous clock. Journal of the Indian Medical Association, 106 (11), pp. 736-740.

Abbas A; Grant PJ; Kearney MT (2008) Role of IGF-1 in glucose regulation and cardiovascular disease. Expert Review of Cardiovascular Therapy, 6 (8), pp. 1135-1149.

Ajjan RA; Grant PJ (2008) The cardiovascular safety of rosiglitazone. Expert Opinion on Drug Safety, 7 (4), pp. 367-376.

Carter AM; Cymbalista CM; Spector TD; Grant PJ; Invest E (2007) Heritability of clot formation, morphology, and lysis - The EuroCLOT study. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 27 , pp. 2783-2789.

Cubbon RM; Gale CP; Grant PJ; Hall AS; Kearney MT (2007) Lower rates of heart failure and death in acute coronary syndromes. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 298 , pp. 969-969.

Vardy ERLC; Rice PJ; Bowie PCW; Holmes JD; Grant PJ; Hooper NM (2007) Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease. JOURNAL OF ALZHEIMERS DISEASE, 12 , pp. 285-290.

Grant PJ (2007) Rosiglitazone and cardiovascular disease: A diabetologist's perspective. Diabetes and Vascular Disease Research, 4 (2), pp. 75-76.

Rice GI; Jones AL; Grant PJ; Carter AM; Turner AJ; Hooper NM (2006) Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study. HYPERTENSION, 48 , pp. 914-920.

Scott EM; Grant PJ (2006) Neel revisited: the adipocyte, seasonality and type 2 diabetes. DIABETOLOGIA, 49 , pp. 1462-1466.

Dunn EJ; Philippou H; Ariens RAS; Grant PJ (2006) Molecular mechanisms involved in the resistance of fibrin to clot lysis by plasmin in subjects with type 2 diabetes mellitus. DIABETOLOGIA, 49 , pp. 1071-1080.

Ajjan R; Grant PJ; Futers TS; Brown J; Carter AM (2006) The association of complement C3 genotype with coronary artery disease, markers of the metabolic syndrome and C3 plasma levels. Thrombosis and Haemostasis, 95 (2), pp. 393-395.

Ajjan RA; Grant PJ; Futers TS; Brown JM; Carter AM (2006) The association of complement C3 genotype with coronary artery disease, markers of the metabolic syndrome and C3 plasma levels. THROMBOSIS AND HAEMOSTASIS, 95 , pp. 393-394.

Rice GI; Jones AL; Grant PJ; Carter AM; Turner AJ; Hooper NM (2006) Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study. Hypertension, 48 (5), pp. 914-920.

Scott EM; Grant PJ (2006) Neel revisited: The adipocyte, seasonality and type 2 diabetes. Diabetologia, 49 (7), pp. 1462-1466.

Standeven KF; Ariens RAS; Grant PJ (2005) The molecular physiology and pathology of fibrin structure/function. BLOOD REVIEWS, 19 , pp. 275-288.

Sullivan CM; Futers TS; Barrett JH; Hudson BI; Freeman MS; Grant PJ (2005) RAGE polymorphisms and the heritability of insulin resistance: The Leeds Family Study. Diabetes and Vascular Disease Research, 2 (1), pp. 42-44.

Grant PJ (2005) Inflammatory, atherothrombotic aspects of type 2 diabetes. CURRENT MEDICAL RESEARCH AND OPINION, 21 , pp. S5-S12.

Reaven GM; Scott EM; Grant PJ; Lowe GDO; Rumley A; Wannamethee SG; Stratmann B; Tschoepe D; Blann A; Juhan-Vague I; Alessi MC; Bailey C (2005) Hemostatic abnormalities associated with obesity and the metabolic syndrome. Journal of Thrombosis and Haemostasis, 3 (5), pp. 1074-1085.

Parry DJ; Grant PJ; Scott DJA (2004) Atherothrombotic risk factor clustering in healthy male relatives of male patients with intermittent claudication. JOURNAL OF VASCULAR SURGERY, 40 , pp. 891-898.

Rice GI; Thomas DA; Grant PJ; Turner AJ; Hooper NM (2004) Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. BIOCHEMICAL JOURNAL, 383 , pp. 45-51.

Scott EM; Ariens RAS; Grant PJ (2004) Genetic and environmental determinants of fibrin structure and function - Relevance to clinical disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 24 , pp. 1558-1566.

Grant PJ (2003) Beneficial effects of metformin on haemostasis and vascular function in man.. Diabetes Metab, 29 (4 Pt 2), pp. 6S44-6S52.

Philippou H; Rance J; Myles T; Hall SW; Ariens RA; Grant PJ; Leung L; Lane DA (2003) Roles of low specificity and cofactor interaction sites on thrombin during factor XIII activation - Competition for cofactor sites on thrombin determines its fate. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 , pp. 32020-32026.

Kain K; Catto AJ; Grant PJ (2003) Associations between insulin resistance and thrombotic risk factors in high-risk South Asian subjects. DIABETIC MEDICINE, 20 , pp. 651-655.

Standeven KF; Grant PJ; Carter AM; Scheiner T; Weisel JW; Ariens RAS (2003) Functional analysis of the fibrinogen A alpha Thr312Ala polymorphism - Effects on fibrin structure and function. CIRCULATION, 107 , pp. 2326-2330.

Winter JP; Gong YY; Grant PJ; Wild CP (2003) Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease. CORONARY ARTERY DISEASE, 14 , pp. 149-153.

Kain K; Blaxill JM; Catto AJ; Grant PJ; Carter AM (2003) Re: "Increased fibrinogen levels among South Asians versus whites in the United Kingdom are not explained by common polymorphisms" - Reply. AMERICAN JOURNAL OF EPIDEMIOLOGY, 157 , pp. 665-665.

Kain K; Carter AM; Bamford JM; Grant PJ; Catto AJ (2003) Gender differences in coagulation and fibrinolysis in white subjects with acute ischemic stroke. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 1 , pp. 390-392.

Freeman MS; Mansfield MW; Barrett JH; Grant PJ (2003) Insulin resistance: an atherothrombotic syndrome - The Leeds family study. THROMBOSIS AND HAEMOSTASIS, 89 , pp. 161-168.

Lim BCB; Ariëns RAS; Carter AM; Weisel JW; Grant PJ (2003) Genetic regulation of fibrin structure and function: Complex gene-environment interactions may modulate vascular risk. Lancet, 361 (9367), pp. 1424-1431.

Winter JP; Gong Y; Grant PJ; Wild CP (2003) Glutathione peroxidase 1 genotype is associated with an increased risk of coronary artery disease. Coronary Artery Disease, 14 (2), pp. 149-153.

Wilson MH; Grant PJ; Kain K; Warner DP; Wild CP (2003) Association between the risk of coronary artery disease in South Asians and a deletion polymorphism in glutathione S-transferase M1. BIOMARKERS, 8 , pp. 43-50.

Kain K; Catto AJ; Young J; Bamford J; Bavington J; Grant PJ (2002) Coagulation factor VII activity, Arg/Gln353 polymorphism and features of insulin resistance in first-degree-relatives of South Asian patients with stroke. THROMBOSIS AND HAEMOSTASIS, 88 , pp. 954-960.

Freeman MS; Mansfield MW; Barrett JH; Grant PJ (2002) Heritability of features of the insulin resistance syndrome in a community-based study of healthy families. DIABETIC MEDICINE, 19 , pp. 994-999.

Kain K; Catto AJ; Grant PJ (2002) Clustering of thrombotic factors with insulin resistance in South Asian patients with ischaemic stroke. THROMBOSIS AND HAEMOSTASIS, 88 , pp. 950-953.

Mills JD; Ariens RAS; Mansfield MW; Grant PJ (2002) Altered fibrin clot structure in the healthy relatives of patients with premature coronary artery disease. CIRCULATION, 106 , pp. 1938-1942.

Vlieg AV; Komanasin N; Ariens RAS; Poort SR; Grant PJ; Bertina RM; Rosendaal FR (2002) Factor XIII Val34Leu polymorphism, factor XIII antigen levels and activity and the risk of deep venous thrombosis. BRITISH JOURNAL OF HAEMATOLOGY, 119 , pp. 169-175.

Ariens RAS; de Lange M; Snieder H; Spector TD; Grant PJ (2002) Activation of coagulation and fibrinolytic system and thrombotic tendency - Reply. LANCET, 360 , pp. 802-802.

Kohler HP; Ariens RAS; Catto AJ; Carter AM; Miller GJ; Cooper JA; Mansfield MW; Standeven KF; Grant PJ (2002) Factor XIII A-subunit concentration predicts outcome in stroke subjects and vascular outcome in healthy, middle-aged men. BRITISH JOURNAL OF HAEMATOLOGY, 118 , pp. 825-832.

Mills JD; Mansfield MW; Grant PJ (2002) Elevated fibrinogen in the healthy male relatives of patients with severe, premature coronary artery disease. EUROPEAN HEART JOURNAL, 23 , pp. 1276-1281.

Kain K; Catto AJ; Young J; Bamford J; Bavington J; Grant PJ (2002) Increased fibrinogen, von Willebrand factor and tissue plasminogen activator levels in insulin resistant South Asian patients with ischaemic stroke. ATHEROSCLEROSIS, 163 , pp. 371-376.

Kain K; Blaxill JM; Catto AJ; Grant PJ; Carter AM (2002) Increased fibrinogen levels among south Asians versus whites in the united kingdom are not explained by common polymorphisms. AMERICAN JOURNAL OF EPIDEMIOLOGY, 156 , pp. 174-179.

Herlihy OM; Barrow BA; Grant PJ; Levy JC (2002) Hyperglycaemic siblings of Type II (non-insulin-dependent) diabetic patients have increased PAI-1, central obesity and insulin resistance compared with their paired normoglycaemic sibling. DIABETOLOGIA, 45 , pp. 635-641.

Mills JD; Mansfield MW; Grant PJ (2002) Tissue plasminogen activator, fibrin D-dimer, and insulin resistance in the relatives of patients with premature coronary artery disease. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 22 , pp. 704-709.

Freeman MS; Mansfield MW; Barrett JH; Grant PJ (2002) Genetic contribution to circulating levels of hemostatic factors in healthy families with effects of known genetic polymorphisms on heritability. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 22 , pp. 506-510.

Hassan A; Lansbury A; Catto AJ; Guthrie A; Spencer J; Craven C; Grant PJ; Bamford JM (2002) Angiotensin converting enzyme insertion/deletion genotype is associated with leukoaraiosis in lacunar syndromes. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 72 , pp. 343-346.

Mills JD; Mansfield MW; Grant PJ (2002) Factor XIII - Circulating levels and the Val34Leu polymorphism in the healthy male relatives of patients with severe coronary artery disease. THROMBOSIS AND HAEMOSTASIS, 87 , pp. 409-414.

Ariens RAS; de Lange M; Snieder H; Boothby M; Spector TD; Grant PJ (2002) Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state. LANCET, 359 , pp. 667-671.

Standeven KF; Ariens RAS; Whitaker P; Ashcroft AE; Weisel JW; Grant PJ (2002) The effect of dimethylbiguanide on thrombin activity, FXIII activation, fibrin polymerization, and fibrin clot formation. DIABETES, 51 , pp. 189-197.

Hoffman MA; Drury S; Hudson B; Gleason MR; Qu W; Lu Y; Lalla E; Chitnis S; Montiero J; Stickland M; Bucciarelli LG; Moser B; Parisien M; Moxley G; Itescu S; Grant PJ; Gregerson PK; Stern DM; Schmidt AM (2002) RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes and Immunity, 3 , pp. 123-135.

Kain K; Young J; Bamford J; Bavington J; Grant PJ; Catto AJ (2002) Determinants of plasminogen activator inhibitor-1 in South Asians with ischaemic stroke. CEREBROVASCULAR DISEASES, 14 , pp. 77-83.

Ariens RAS; de Lange M; Snieder H; Spector TD; Grant PJ (2002) Activation of coagulation and fibrinolytic system and thrombotic tendency. The Lancet, 360 (9335), pp. pp.801.

Lansbury AJ; Grant PJ; Catto AJ (2002) Atherothrombotic risk factors in subjects with a family history of stroke. CEREBROVASCULAR DISEASES, 14 , pp. 153-160.

Hudson BI; Stickland MH; Grant PJ; Futers TS (2001) Characterization of allelic and nucleotide variation between the RAGE gene on chromosome 6 and a homologous pseudogene sequence to its 5 ' regulatory region on chromosome 3 - Implications for polymorphic studies in diabetes. DIABETES, 50 , pp. 2646-2651.

Warner D; Mansfield M; Grant PJ (2001) Coagulation factor XIII levels in UK Asian subjects with type 2 diabetes mellitus and coronary artery disease. THROMBOSIS AND HAEMOSTASIS, 86 , pp. 1117-1118.

Costa M; Grant PJ; Rice GI; Futers TS; Medcalf RL (2001) Human endothelial cell-derived nuclear proteins that recognise polymorphic DNA elements in the von Willebrand factor gene promoter include YY1. THROMBOSIS AND HAEMOSTASIS, 86 , pp. 672-679.

Kain K; Catto AJ; Carter AM; Young J; Bamford J; Bavington J; Grant PJ (2001) Decreased fibrinolytic potential in South Asian women with ischaemic cerebrovascular disease. BRITISH JOURNAL OF HAEMATOLOGY, 114 , pp. 155-161.

Kain K; Catto AJ; Grant PJ (2001) Impaired fibrinolysis and increased fibrinogen levels in South Asian subjects. ATHEROSCLEROSIS, 156 , pp. 457-461.

Rice GI; Futers TS; Grant PJ (2001) Identification of novel polymorphisms within the protein Z gene, haplotype distribution and linkage analysis. THROMBOSIS AND HAEMOSTASIS, 85 , pp. 1123-1124.

Hudson BI; Stickland MH; Futers TS; Grant PJ (2001) Effects of novel polymorphisms in the RAGE gene on transcriptional regulation and their association with diabetic retinopathy. DIABETES, 50 , pp. 1505-1511.

Amini-Nekoo A; Futers TS; Moia M; Mannucci PM; Grant PJ; Ariens RAS (2001) Analysis of the tissue factor pathway inhibitor gene and antigen levels in relation to venous thrombosis. BRITISH JOURNAL OF HAEMATOLOGY, 113 , pp. 537-543.

Kain K; Catto AJ; Young J; Bamford J; Bavington J; Grant PJ (2001) Insulin resistance and elevated levels of tissue plasminogen activator in first-degree relatives of South Asian patients with ischemic cerebrovascular disease. STROKE, 32 , pp. 1069-1073.

Catto AJ; Ariens RAS; Grant PJ (2001) Response: Relationship between FXIIIV34L and Factor V leiden in patients with venous thrombosis. BLOOD, 97 , pp. 1895-1895.

Kohler HP; Ariens RAS; Mansfield MW; Whitaker P; Grant PJ (2001) Factor XIII activity and antigen levels in patients with coronary artery disease. THROMBOSIS AND HAEMOSTASIS, 85 , pp. 569-570.

Warner D; Mansfield MW; Grant PJ (2001) Coagulation factor XIII and cardiovascular disease in UK Asian patients undergoing coronary angiography. THROMBOSIS AND HAEMOSTASIS, 85 , pp. 408-411.

de Lange M; Snieder H; Ariens RAS; Spector TD; Grant PJ (2001) The genetics of haemostasis: a twin study. LANCET, 357 , pp. 101-105.

Catto AJ; Ariens RAS; Grant PJ (2001) Relationship between FXIIIVal34Leu and Factor V Leiden in patients with venous thrombosis (invited response). Blood, 97 , pp. 1894-1896.

Ariens RAS; Philippou H; Nagaswami C; Weisel JW; Lane DA; Grant PJ (2000) The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure. Blood, 96 (3), pp. 988-995.

Ashcroft AE; Grant PJ; Ariens RAS (2000) A study of human coagulation factor XIII A-subunit by electrospray ionisation mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 14 , pp. 1607-1611.

Catto AJ; Mccormack LJ; Mansfield MW; Carter AM; Bamford JM; Robinson P; Grant PJ (2000) Apolipoprotein E: polymorphism in cerebrovascular disease. Acta Neurologica Scandinavica, 101 , pp. 399-404.

Wilson MH; Grant PJ; Hardie LJ; Wild CP (2000) Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. The FASEB Journal, 14 (5), pp. 791-796.

Mansfield MW; Kohler HP; Ariens RAS; Mccormack LJ; Grant PJ (2000) Circulating levels of coagulation factor XIII in subjects with type 2 diabetes and in their first-degree relatives [letter]. Diabetes Care, 23 (5), pp. 703-705.

Cooper JM; Grant PJ (2000) Role of hemostatic gene polymorphisms in venous and arterial thrombotic disease. [Review] [226 refs] . Blood, 95 (5), pp. 1517-1532.

Ariens RAS; Philippou H; Nagaswami C; Weisel JW; Lane DA; Grant PJ (2000) The factor XIII V34L polymorphism accelerates thrombin activation of factor XIII and affects cross-linked fibrin structure. Blood, 96 (3), pp. 988-995.

Carter AM; Catto AJ; Kohler HP; Ariens RAS; Stickland M; Grant PJ (2000) alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism. Blood, 96 (3), pp. 1177-1179.

Warner DL; Catto AJ; Kunz G; Ireland H; Grant PJ; Lane DA (2000) The thrombomodulin gene mutation G(127)-->A (Ala25Thr) and cerebrovascular disease. Cerebrovascular Diseases, 10 (5), pp. 359-363.

Kohler HP; Mansfield MW; Clark PS; Grant PJ (1999) Interaction between insulin resistance and factor XIII Val34Leu in patients with coronary artery disease. Thrombosis and Haemostasis, 82 , pp. 1202-1203.

Kohler HP; Futers TS; Grant PJ (1999) Prevalence of three common polymorphisms in the A-subunit gene of factor XIII in patients with coronary artery disease. . Thrombosis and Haemostasis, 81 (4), pp. 511-515.

Ariens RAS; Kohler HP; Mansfield MW; Grant PJ (1999) Subunit antigen and activity levels of blood coagulation factor XIII in healthy individuals. Relation to sex, age, smoking, and hypertension. . Arteriosclerosis, Thrombosis, and Vascular Biology, 19 (8), pp. 2012-2016.

Catto AJ; Kohler HP; Coore J; Mansfield MW; Stickland M; Grant PJ (1999) Association of a common polymorphism in the factor XIII gene with venous thrombosis. . Blood, 93 (3), pp. 906-908.

Carter AM; Catto AJ; Grant PJ (1999) Association of the alpha-fibrinogen Thr312Ala polymorphism with post stroke mortality in subjects with atrial fibrillation.. Circulation (Baltimore), 99 (18), pp. 2423-2426.

Kohler HP; Futers TS; Grant PJ (1999) FXII (46C-->T) polymorphism and in vivo generation of FXII activity--gene frequencies and relationship in patients with coronary artery disease. . Thrombosis and Haemostasis, 81 (5), pp. 745-747.

Rice G; Foy C; Grant PJ (1999) Angiotensin converting enzyme and angiotensin II type 1-receptor gene polymorphisms and risk of ischaemic heart disease. . Cardiovascular Research, 41 (3), pp. 746-753.

Kohler HP; Grant PJ (1999) The role of factor XIIIVal34Leu in cardiovascular disease. [Review] [44 refs] . QJM, 92 (2), pp. 67-72.

Grant PJ; Humphries S (1999) Genetic determinants of arterial thrombosis [Review] [185 refs]. Baillieres Best Practice in Clinical Haematology, 12 (3), pp. 505-532.

Carter AM; Catto AJ; Bamford JM; Grant PJ (1999) Association of the platelet glycoprotein IIb HPA-3 polymorphism with survival after acute ischemic stroke. . Stroke, 30 (12), pp. 2606-2611.

Wartiovaara U; Perola M; Mikkola H; Totterman K; Savolainen V; Penttila A; Grant PJ; Tikkanen MJ; Vartiainen E; Karhunen PJ; Peltonen L; Palotie A (1999) Association of FXIII Val34Leu with decreased risk of myocardial infarction in Finnish males. . Atherosclerosis, 142 (2), pp. 295-300.

Mansfield MW; Catto AJ; Carter AM; Grant PJ (1998) Fibrinolytic measurements in type 2 diabetic patients with acute cerebral infarction. . Diabetic Medicine, 15 (11), pp. 953-957.

Salooja N; Catto AJ; Carter AM; Tudenham EG; Grant PJ (1998) Methylene tetrahydrofolate reductase C677T genotype and stroke. . Clinical and Laboratory Haematology, 20 (6), pp. 357-361.

Carter AM; Catto AJ; Bamford JM; Grant PJ (1998) Platelet GP IIIa PlA and GP Ib variable number tandem repeat polymorphisms and markers of platelet activation in acute stroke. . Arteriosclerosis, Thrombosis, and Vascular Biology, 18 (7), pp. 1124-1131.

Carter AM; Catto AJ; Grant PJ (1998) Elevated levels of t-PA antigen in subjects with coronary artery disease and acute cerebrovascular disease. Thrombosis and Haemostasis, 80 , pp. 632-636.

Bannan S; Mansfield MW; Grant PJ (1998) Soluble vascular cell adhesion molecule-1 and E-selectin levels in relation to vascular risk factors and to E-selectin genotype in the first degree relatives of NIDDM patients and in NIDDM patients. . Diabetologia, 41 (4), pp. 460-466.

Hudson BI; Stickland M; Grant PJ (1998) Identification of polymorphisms in the receptor for advanced glycation end products (RAGE) gene: prevalence in type 2 diabetes and ethnic groups. [Review] [10 refs] . Diabetes, 47 (7), pp. 1155-1157.

Nagi D; Mohamed-Ali V; Yudkin JS; Grant PJ; Knowler WC (1998) Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians. . Metabolism: Clinical and Experimental, 47 (5), pp. 622-626.

Grant PJ (1998) Metformin reduces circulating factor VII concentrations in patients with type 2 diabetes mellitus [letter]. . Thrombosis and Haemostasis, 80 (1), pp. 209-210.

Kohler HP; Carter AM; Stickland M; Grant PJ (1998) Levels of activated FXII in survivors of myocardial infarction--association with circulating risk factors and extent of coronary artery disease. . Thrombosis and Haemostasis, 79 (1), pp. 14-18.

Rice G; Grant PJ (1998) FVIII coagulant activity and antigen in subjects with ischaemic heart disease. . Thrombosis and Haemostasis, 80 (5), pp. 757-762.

Catto AJ; Kohler HP; Bannan S; Stickland M; Carter AM; Grant PJ (1998) Factor XIII Val 34 Leu: a novel association with primary intracerebral hemorrhage. . Stroke, 29 (4), pp. 813-816.

Kohler HP; Grant PJ (1998) Clustering of haemostatic risk factors with FXIIIVal34Leu in patients with myocardial infarction [letter]. . Thrombosis and Haemostasis, 80 (5), pp. 862.

Mccormack LJ; Kain K; Catto AJ; Kohler HP; Stickland M; Grant PJ (1998) Prevalence of FXIII V34L in populations with different cardiovascular risk [letter]. . Thrombosis and Haemostasis, 80 (3), pp. 523-524.

Bailey CJ; Grant PJ (1998) The UK Prospective Diabetes Study [letter; comment]. . The Lancet, 352 (9144), pp. 1932, 1934.

Grant PJ; Carter AM (1998) Platelet P1a polymorphism, myocardial infarction and extent of coronary artery disease. Circulation (Baltimore), 98 , pp. 826-827.

Ossei-Gerning N; Wilson J; Grant PJ (1998) Sex differences in coagulation and fibrinolysis in subjects with coronary artery disease. . Thrombosis and Haemostasis, 79 (4), pp. 736-740.

Carter AM; Mansfield MW; Grant PJ (1998) Polymorphisms of platelet glycoproteins in relation to macrovascular disease in type 2 diabetes mellitus. . Diabetic Medicine, 15 (4), pp. 315-319.

Carter AM; Catto AJ; Grant PJ (1998) Determinants of tPA antigen and associations with coronary artery disease and acute cerebrovascular disease. . Thrombosis and Haemostasis, 80 (4), pp. 632-636.

Kohler HP; Stickland M; Ossei-Gerning N; Carter AM; Mikkola H; Grant PJ (1998) Association of a common polymorphism in the factor XIII gene with myocardial infarction. . Thrombosis and Haemostasis, 79 (1), pp. 8-13.

McCormack LJ; Semple JI; Stickland MH; Barrett JH; Grant PJ (1998) The effect of number of days in culture and plasminogen activator inhibitor-1 (PAI-1) 4G/5G genotype on PAI-1 antigen release by cultured human umbilical vein endothelial cells. Thrombosis Research, 92 (5), pp. 199-206.

Kohler HP; Ariens RAS; Whitaker P; Grant PJ (1998) A common coding polymorphism in the FXIII A-subunit gene (FXIIIVal34Leu) affects cross-linking activity [letter]. . Thrombosis and Haemostasis, 80 (4), pp. 704.

Grant PJ (1997) Plasminogen activator inhibitor-1 gene and myocardial infarction [letter; comment]. . Circulation (Baltimore), 96 (10), pp. 3796-3797.

Matalon A; Grant PJ (1997) PCR-RFLP detection of PAI-2 gene variants: prevalence in ethnic groups and disease relationship in patients undergoing coronary angiography. . Thrombosis and Haemostasis, 77 (5), pp. 955-958.

Lansbury AJ; Catto AJ; Carter AM; Grant PJ (1997) The Paraoxonase GIn/Arg polymorphism and cerebrovascular disease. . Cerebrovascular Diseases, 7 , pp. 353-356.

Catto AJ; Carter AM; Barrett JH; Bamford J; Rice PJ; Grant PJ (1997) Von Willebrand factor and factor VIII:C in acute cerebrovascular disease. Relationship to stroke, subtype and mortality. Thrombosis and Haemostasis, 77 (6), pp. 1104-1108.

Drouet LO; Mccormack LJ; Grant PJ (1997) Incidence of Arg506 --> Gln mutation (factor V Leiden) in Pima Indians [letter; comment]. . Thrombosis and Haemostasis, 78 (2), pp. 961-962.

Catto AJ; Carter AM; Barrett JH; Stickland MH; Davies JA; Grant PJ (1997) Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G promoter polymorphism and levels in subjects with cerebrovascular disease . Thrombosis and Haemostasis, 77 (4), pp. 730-734.

Foy CA; Rice G; Mansfield MW; Grant PJ (1997) Angiotensin-converting enzyme (ACE) gene polymorphisms in patients characterised by coronary angiography. . Human Genetics, 100 (3-4), pp. 420-425.

Carter AM; Przepiorka D; Wilson IJ; Grant PJ (1997) Association of the platelet Pl(A) polymorphism of glycoprotein IIb/IIIa and the fibrinogen Bbeta 448 polymorphism with myocardial infarction and extent of coronary artery disease. . Circulation (Baltimore), 96 (5), pp. 1424-1431.

Moayyedi P; Carter AM; Catto AJ; Heppell RM; Grant PJ (1997) Validation of a rapid whole blood test for the diagnosis of helicobacter pylori infection. British Medical Journal, 314 , pp. 119.

Turnbull DM; Mansfield MW; Grant PJ (1997) Plasminogen activator inhibitor-1 (PAI-1) promoter 4G/5G genotype and plasma levels in relation to a history of myocardial infarction in patients characterized by coronary angiography.. Arteriosclerosis, Thrombosis, and Vascular Biology, 17 (1), pp. 33-37.

Trigwell PJ; Grant PJ; House AO (1997) Motivation and glycemic control in diabetes mellitus . Journal of Psychosomatic Research, 43 (3), pp. 307-315.

Bash KL; Mansfield MW; Grant PJ (1997) Insulin receptor substrate-1 gene polymorphism and cardiovascular risk in non-insulin dependent diabetes mellitus and patients undergoing coronary angiography. . Clinical and Laboratory Haematology, 19 (2), pp. 123-128.

New JP; Grant PJ (1997) Genes and the development of vascular disease. [Review] [32 refs] . Postgraduate Medical Journal, 73 (859), pp. 271-278.

Mansfield MW; Padhani AR; Grant PJ (1997) PAI-1 concentrations in first-degree relatives of patients with non-insulin-dependent diabetes: metabolic and genetic associations. . Thrombosis and Haemostasis, 77 (2), pp. 357-361.

Carter AM; Grant PJ (1997) Vascular homeostasis, adhesion molecules, and macrovascular disease in non-insulin-dependent diabetes mellitus. [Review] [104 refs] . Diabetic Medicine, 14 (6), pp. 423-432.

Saboorian MH; Mccormack LJ; Grant PJ (1997) Diabetic retinopathy, promoter (4G/5G) polymorphism of PAI-1 gene, and PAI-1 activity in Pima Indians with type 2 diabetes [see comments]. . Diabetes Care, 20 (8), pp. 1304-1309.

Grant PJ (1997) Polymorphisms of coagulation/fibrinolysis genes: gene environment interactions and vascular risk. [Review] [37 refs] . Prostaglandins, Leukotrienes and Essential Fatty Acids, 57 (4-5), pp. 473-477.

Carter AM; Catto AJ; Davis MM; Grant PJ (1997) Gender-specific associations of the fibrinogen B beta 448 polymorphism, fibrinogen levels, and acute cerebrovascular disease. . Arteriosclerosis, Thrombosis, and Vascular Biology, 17 (3), pp. 589-594.

Lubina J; Moayyedi P; Smith S; Wilson J; Grant PJ (1997) Helicobacter pylori infection is related to atheroma in patients undergoing coronary angiography. . Cardiovascular Research, 35 (1), pp. 120-124.

Heywood DM; Carter AM; Catto AJ; Grant PJ (1997) Polymorphisms of the factor VII gene and circulating FVII:C levels in relation to acute cerebrovascular disease and poststroke mortality. . Stroke, 28 (4), pp. 816-821.

Rice G; Tarrel J; Grant PJ (1997) The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease. . Coronary Artery Disease, 8 (11-12), pp. 677-682.

Barrett JH; Foy CA; Grant PJ (1996) Commingling analysis of the distribution of a phenotype conditioned on two marker genotypes: Application to plasma angiotensin-converting enzyme levels. Genetic Epidemiology, 13 (6), pp. 615-625.

Catto AJ; Carter AM; Barrett JH; D'Amore A; Davies JA; Grant PJ (1996) Angiotensin-converting enzyme insertion/deletion polymorphism and cerebrovascular disease. . Stroke, 27 (3), pp. 573.

Carter AM; Mansfield MW; Wood R; Grant PJ (1996) Beta-fibrinogen gene-455 G/A polymorphism and fibrinogen levels. Risk factors for coronary artery disease in subjects with NIDDM. . Diabetes Care, 19 (11), pp. 1265-1268.

Carter AM; Ossei-Gerning N; Grant PJ (1996) Platelet glycoprotein IIIa PlA polymorphism in young men with myocardial infarction [letter; comment]. . The Lancet, 348 (9025), pp. 485-486.

Catto AJ; Carter AM; Grant PJ (1996) Factor V Leiden mutation and completed stroke [letter; comment]. . Stroke, 27 (3), pp. 573.

Mccormack LJ; Nagi DK; Mansfield MW; Grant PJ (1996) Promoter (4G/5G) plasminogen activator inhibitor-1 genotype in Pima Indians: relationship to plasminogen activator inhibitor-1 levels and features of the insulin resistance syndrome. . Diabetologia, 39 (12), pp. 1512-1518.

Riechmann L; Mansfield MW; Grant PJ (1996) Levels of von Willebrand factor, insulin resistance syndrome, and a common vWF gene polymorphism in non-insulin-dependent (type 2) diabetes mellitus. . Diabetic Medicine, 13 (8), pp. 720-725.

Carter AM; Moayyedi P; Catto AJ; Elder JB; Grant PJ (1996) The influence of Helicobacter pylori status on circulating levels of the coagulation factors fibrinogen, von Willebrand factor, factor VII, and factor VIII. . Helicobacter, 1 (1), pp. 65-69.

Dexter SPL; Griffith JP; Grant PJ; McMahon MJ (1996) Activation of coagulation and fibrinolysis in open and laparoscopic cholecystectomy. . Surgical Endoscopy, 10 (11), pp. 1069-1074.

Yearwood GD; Mansfield MW; Grant PJ (1996) Factor VII gene polymorphisms, factor VII:C levels and features of insulin resistance in non-insulin-dependent diabetes mellitus. . Thrombosis and Haemostasis, 75 (3), pp. 401-406.

Randall CL; Grant PJ (1996) Association of factor VII:C levels with environmental and genetic factors in patients with ischaemic heart disease and coronary atheroma characterised by angiography. . Thrombosis and Haemostasis, 76 (2), pp. 161-165.

Mansfield MW; Shikanai K; Grant PJ (1996) Circulating levels of factor VII, fibrinogen, and von Willebrand factor and features of insulin resistance in first-degree relatives of patients with NIDDM. . Circulation (Baltimore), 94 (9), pp. 2171-2176.

Foy CA; McCormack LJ; Knowler WC; Barrett JH; Catto A; Grant PJ (1996) The angiotensin-I converting enzyme (ACE) gene I/D polymorphism and ACE levels in Pima Indians. Journal of Medical Genetics, 33 (4), pp. 336-337.

Grant PJ (1996) The effect of high and medium dose metformin therapy on cardiovascular risk factors in patients with type 2 diabetes mellitus.. Diabetes Care, 19 , pp. 64-66.

Catto A; Carter AM; Barrett JH; Stickland M; Bamford J; Davies JA; Grant PJ (1996) Angiotensin-converting enzyme insertion/deletion polymorphism and cerebrovascular disease. Stroke, 27 (3), pp. 435-440.

Carter AM; Ossei-Gerning N; Grant PJ (1996) Platelet glycoprotein IIIa PlA polymorphism and myocardial infarction [letter; comment]. . New England Journal of Medicine, 335 (14), pp. 1072-1073.

Grant PJ (1996) The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type II diabetes. . Diabetes Care, 19 (1), pp. 64-66.

Mansfield MW; Steptoe A; Grant PJ (1996) Sex differences in coagulation and fibrinolysis in white subjects with non-insulin-dependent diabetes mellitus. . Arteriosclerosis, Thrombosis, and Vascular Biology, 16 (1), pp. 160-164.

Grant PJ (1995) Environmental and genetic factors in relation to elevated circulating levels of plasminogen activator inhibitor-1 in Caucasian patients with non-insulin dependent diabetes mellitus.. Thrombosis and Haemostasis, 74 , pp. 842-847.

Catto A; Carter A; Ireland H; Bayston TA; Philippou H; Barrett J; Lane DA; Grant PJ (1995) Factor V Leiden gene mutation and thrombin generation in relation to the development of acute stroke. Arteriosclerosis, Thrombosis, and Vascular Biology, 15 (6), pp. 783-785.

Grant PJ Diabetes and Vascular Disease Research(Editorship). Diabetes and Vascular Disease Research, .