Professor Eileen Ingham
BSc, PhD 1979, Leeds.
Professor of Medical Immunology
Institute of Molecular and Cellular Biology
Background: BSc (Leeds), PhD (Leeds). Professor of Medical Immunology (2000-); Deputy Director iMBE; International Editor, Biomaterials (2000-); BBSRC EBS Committee member (2004 - 2007); member of EPSRC College
Office: Garstang 7.60a
Phone: +44(0) 113 34 35691
Email: e.ingham@leeds.ac.uk
Centre membership:
- The Antimicrobial Research Centre
- The Centre for Molecular Nanoscience
- The Institute of Medical and Biological Engineering
- The Multidisciplinary Cardiovascular Research Centre (MCRC)
- The Skin Research Centre
You can read more about Professor Ingham's interests here:
www.fbs.leeds.ac.uk/research/bioeng.htm
|
Research Interests
Tissue Replacement and Regeneration, Joint prostheses, Tissue engineering
My research interests are mainly focused upon the immunological aspects of tissue replacement (prosthetic hips, knees, spinal discs) and tissue engineering. Together with John Fisher (Mechanical Engineering), I am a recipient of a prestigious EPSRC Portfolio Award on Tissue Replacement and Regeneration. Research is carried out in the Institute of Medical & Biological Engineering, encompassing multidisciplinary research across medicine, biology and engineering.
Joint prostheses
Total joint replacement was the most successful surgical procedure of the 20th century. However, these prostheses, made from UHMWPE on metal/ceramic, require replacement after 10–25 years due to osteolysis (Figure 1). This is an immunological problem caused by the host macrophage response to particulate UHMWPE wear debris (Figure 2) generated at the articulating surfaces. We study particles generated by alternative materials and designs for joint replacement, being tested in simulators by engineers, and from patients. We isolate and characterize the particles, which can be as small as 10 nm, and then investigate the biological effects of the particles on cells (macrophages, stromal cells, lymphocytes) in the laboratory and in small-animal models to predict the in vivo biocompatibility of the materials/designs.
Tissue engineering
Tissue-engineering research is focused on immunocompatible de-cellularized soft-tissue scaffolds. We have developed methods for the de-cellularization of allogeneic and xenogeneic tissues including aortic roots (Figure 3), patella tendons, pericardium, bladder, vessels and amnion. These scaffolds are being investigated for their capacity to regenerate into living tissues (Figure 4). To study the regeneration of the scaffolds seeded with cells in the laboratory we have designed and developed novel physiological simulation systems for the culture of three-dimensional tissues under appropriate physical stimulation.
Tissue-engineering projects also encompass the development of in vitro skin models for studies of cutaneous microbial interactions, in collaboration with the Skin Research Centre.
More information: www.imbe.org.uk
Studentship information
Undergraduate project topics:
- Tissue engineering, immunological reactions to biomaterials. Immunology of skin micro-organisms.
Postgraduate studentship areas:
- Tissue Engineering and the Immunology of Skin Microorganisms
See also:
Publications
Vicars R; Prokopovich P; Brown TD; Tipper JL; Ingham E; Fisher J; Hall RM The effect of anterior-posterior shear on the wear of CHARITI total disc replacement Spine 37 E528-E534, 2012
Michalopoulos E; Knight RL; Korossis S; Kearney JN; Fisher J; Ingham E Development of Methods for Studying the Differentiation of Human Mesenchymal Stem Cells Under Cyclic Compressive Strain TISSUE ENGINEERING PART C-METHODS 18 252-262, 2012
DOI:10.1089/ten.tec.2011.0347
Wilshaw S; Rooney P; Berry H; Kearney JN; Homer-Vanniasinkam S; Fisher J; Ingham E Development and Characterization of Acellular Allogeneic Arterial Matrices TISSUE ENGINEERING PART A 18 471-483, 2012
DOI:10.1089/ten.tea.2011.0287
Damion RA; Pawaskar SS; Ries ME; Ingham E; Williams S; Jin Z; Radjenovic A Spin-lattice relaxation rates and water content of freeze-dried articular cartilage OSTEOARTHRITIS AND CARTILAGE 20 184-190, 2012
DOI:10.1016/j.joca.2011.12.005
Taylor SD; Tsiridis E; Ingham E; Jin Z; Fisher J; Williams S Comparison of human and animal femoral head chondral properties and geometries PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 226 55-62, 2012
DOI:10.1177/0954411911428717
Durham ER; Ingham E; Russell SJ Technique for internal channelling of hydroentangled nonwoven scaffoldsto enhance cell penetration. J Biomater Appl -, 2012
DOI:10.1177/0885328212445077
Tatterton M; Wilshaw SP; Ingham E; Homer-Vanniasinkam S The use of antithrombotic therapies in reducing synthetic small-diameter vascular graft thrombosis. Vasc Endovascular Surg 46 212-222, 2012
DOI:10.1177/1538574411433299
Owen K; Wilshaw S; Homer-Vanniasinkam S; Bojar RA; Berry H; Ingham E Assessment of the Antimicrobial Activity of Acellular Vascular Grafts European Journal of Vascular and Endovascular Surgery -, 2012
Owen K; Wilshaw S; Homer-Vanniasinkam S; Bojar RA; Berry H; Ingham E Assessment of the antimicrobial activity of acellular vascular grafts European Journal of Vascular and Endovascular Surgery 43 573-581, 2012
Figgitt M; Newson R; Leslie I; Fisher J; Ingham E; Case C Genomic instability induced by orthopaedic wear debris in cultured human fibroblasts TOXICOLOGY 290 115-116, 2011
DOI:10.1016/j.tox.2011.09.027
Kheir E; Stapleton T; Shaw D; Jin Z; Fisher J; Ingham E Development and characterization of an acellular porcine cartilage bone matrix for use in tissue engineering JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 99A 283-294, 2011
DOI:10.1002/jbm.a.33171
Sood A; Salih S; Roh D; Lacharme-Lora L; Parry M; Hardiman B; Keehan R; Grummer R; Winterhager E; Gokhale PJ; Andrews PW; Abbott C; Forbes K; Westwood M; Aplin JD; Ingham E; Papageorgiou I; Berry M; Liu J; Dick AD; Garland RJ; Williams N; Singh R; Simon AK; Lewis M; Ham J; Roger L; Baird DM; Crompton LA; Caldwell MA; Swalwell H; Birch-Machin M; Lopez-Castejon G; Randall A; Lin H; Suleiman M; Evans WH; Newson R; Case CP Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness NATURE NANOTECHNOLOGY 6 824-833, 2011
DOI:10.1038/NNANO.2011.188
Maude S; Miles DE; Felton SH; Ingram J; Carrick LM; Wilcox RK; Ingham E; Aggeli A De novo designed positively charged tape-forming peptides: self-assembly and gelation in physiological solutions and their evaluation as 3D matrices for cell growth SOFT MATTER 7 8085-8099, 2011
DOI:10.1039/c0sm00974a
Bullers S; Berry H; Ingham E; Southgate J The role of macrophages in biomaterial-tissue regeneration, 2011
Fisher J; Jin Z; Ingham E; Jennings L; Tipper J; Williams S Bearings: Tribological Aspects: To Wear or Not to Wear In The Corail Hip System: A practical approach based on 25 years of experience , 2011
Pawaskar SS; Ingham E; Fisher J; Jin Z Fluid load support and contact mechanics of hemiarthroplasty in the natural hip joint MEDICAL ENGINEERING&PHYSICS 33 96-105, 2011
DOI:10.1016/j.medengphy.2010.09.009
Stapleton TW; Ingram J; Fisher J; Ingham E Investigation of the Regenerative Capacity of an Acellular Porcine Medial Meniscus for Tissue Engineering Applications TISSUE ENGINEERING PART A 17 231-242, 2011
DOI:10.1089/ten.tea.2009.0807
Pawaskar SS; Grosland NM; Ingham E; Fisher J; Jin Z Hemiarthroplasty of hip joint: An experimental validation using porcine acetabulum JOURNAL OF BIOMECHANICS 44 1536-1542, 2011
DOI:10.1016/j.jbiomech.2011.02.140
Kyle S; McPherson MJ; Aggeli A; Ingham E WITHDRAWN: The effect of molecular design on the physical and biological properties of complementary self-assembling peptides. Biomaterials -, 2011
DOI:10.1016/j.biomaterials.2011.05.082
Wang L; Korossis S; Fisher J; Ingham E; Jin Z Prediction of Oxygen Distribution in Aortic Valve Leaflet Considering Diffusion and Convection JOURNAL OF HEART VALVE DISEASE 20 442-448, 2011
Edwards SL; Church JS; Alexander DLJ; Russell SJ; Ingham E; Ramshaw JAM; Werkmeister JA Modeling Tissue Growth Within Nonwoven Scaffolds Pores TISSUE ENGINEERING PART C-METHODS 17 123-130, 2011
DOI:10.1089/ten.tec.2010.0182
Edwards S; Church JS; Alexander DLJ; Russell SJ; Ingham E; Ramshaw JAM; Werkmeister JA Modeling Tissue Growth Within Nonwoven Scaffolds Pores Tissue Engineering. Part C. Methods 17 123-130, 2011
DOI:10.1089/ten.tec.2010.0182
Kyle S; Aggeli A; Ingham E; McPherson MJ Recombinant self-assembling peptides as biomaterials for tissue engineering BIOMATERIALS 31 9395-9405, 2010
DOI:10.1016/j.biomaterials.2010.08.051
Parry MC; Bhabra G; Sood A; Machado F; Cartwright L; Saunders M; Ingham E; Newson R; Blom AW; Case CP Thresholds for indirect DNA damage across cellular barriers for orthopaedic biomaterials BIOMATERIALS 31 4477-4483, 2010
DOI:10.1016/j.biomaterials.2010.02.038
Figgitt M; Newson R; Leslie IJ; Fisher J; Ingham E; Case CP The genotoxicity of physiological concentrations of chromium (Cr(III) and Cr(VI)) and cobalt (Co(II)): An in vitro study MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 688 53-61, 2010
DOI:10.1016/j.mrfmmm.2010.03.008
Vicars R; Hyde PJ; Brown TD; Tipper JL; Ingham E; Fisher J; Hall RM The effect of anterior-posterior shear load on the wear of ProDisc-L TDR EUROPEAN SPINE JOURNAL 19 1356-1362, 2010
DOI:10.1007/s00586-010-1396-8
Luo Y; McCann L; Ingham E; Jin Z; Ge S; Fisher J Polyurethane as a potential knee hemiarthroplasty biomaterial: an in-vitro simulation of its tribological performance PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 224 415-425, 2010
DOI:10.1243/09544119JEIM657
Fisher J; Jennings LM; Galvin AL; Jin ZM; Stone MH; Ingham E 2009 Knee Society Presidential Guest Lecture Polyethylene Wear in Total Knees CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 468 12-18, 2010
DOI:10.1007/s11999-009-1033-1
Wang M; Radjenovic A; Stapleton TW; Venkatesh R; Williams S; Ingham E; Fisher J; Jin Z A novel and non-destructive method to examine meniscus architecture using 9.4 Tesla MRI OSTEOARTHRITIS AND CARTILAGE 18 1417-1420, 2010
DOI:10.1016/j.joca.2010.08.009
Bullers S; Berry H; Ingham E; Southgate J The host response to porcine-derived biomaterials - the role of the macrophage, 2010
Galvin AL; Jennings LM; Tipper JL; Ingham E; Fisher J Wear and creep of highly crosslinked polyethylene against cobalt chrome and ceramic femoral heads PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 224 1175-1183, 2010
DOI:10.1243/09544119JEIM741
Ingham E Medical implants, wear nanoparticles and biological response MUTAGENESIS 25 639-639, 2010
McCann L; Ingham E; Jin Z; Fisher J An investigation of the effect of conformity of knee hemiarthroplasty designs on contact stress, friction and degeneration of articular cartilage: A tribological study JOURNAL OF BIOMECHANICS 42 1326-1331, 2009
DOI:10.1016/j.jbiomech.2009.03.028
Bhabra G; Sood A; Fisher B; Cartwright L; Saunders M; Evans WH; Surprenant A; Lopez-Castejon G; Mann S; Davis SA; Hails LA; Ingham E; Verkade P; Lane J; Heesom K; Newson R; Case CP Nanoparticles can cause DNA damage across a cellular barrier NATURE NANOTECHNOLOGY 4 876-883, 2009
DOI:10.1038/NNANO.2009.313
Al-Refu K; Edward S; Ingham E; Goodfield M Hair follicle stem cells in the pathogenesis of the scarring process in cutaneous lupus erythematosus, 2009
Al-Refu K; Edward S; Ingham E; Goodfield M Expression of hair follicle stem cells detected by cytokeratin 15 stain: implications for pathogenesis of the scarring process in cutaneous lupus erythematosus BRITISH JOURNAL OF DERMATOLOGY 160 1188-1196, 2009
DOI:10.1111/j.1365-2133.2009.09074.x
Wilshaw S; Burke D; Fisher J; Ingham E Investigation of the Antiadhesive Properties of Human Mesothelial Cells Cultured In Vitro on Implantable Surgical Materials JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 88B 49-60, 2009
DOI:10.1002/jbm.b.31148
Rimmer S; Wilshaw S; Pickavance P; Ingham E Cytocompatibility of poly(1,2 propandiol methacrylate) copolymer hydrogels and conetworks with or without alkyl amine functionality BIOMATERIALS 30 2468-2478, 2009
DOI:10.1016/j.biomaterials.2009.01.041
Kyle S; Aggeli A; Ingham E; McPherson MJ Production of self-assembling biomaterials for tissue engineering TRENDS IN BIOTECHNOLOGY 27 423-433, 2009
DOI:10.1016/j.tibtech.2009.04.002
Korossis S; Bolland F; Southgate J; Ingham E; Fisher J Regional biomechanical and histological characterisation of the passive porcine urinary bladder: Implications for augmentation and tissue engineering strategies BIOMATERIALS 30 266-275, 2009
DOI:10.1016/j.biomaterials.2008.09.034
Wang L; Wilshaw S; Korossis S; Fisher J; Jin Z; Ingham E Factors Influencing the Oxygen Consumption Rate of Aortic Valve Interstitial Cells: Application to Tissue Engineering TISSUE ENGINEERING PART C-METHODS 15 355-363, 2009
DOI:10.1089/ten.tec.2008.0415
Katta J; Jin Z; Ingham E; Fisher J Chondroitin sulphate: an effective joint lubricant? OSTEOARTHRITIS AND CARTILAGE 17 1001-1008, 2009
DOI:10.1016/j.joca.2009.02.010
Al-Refu K; Edward S; Ingham E; Goodfield M Alterations in the basement membrane zone in cutaneous lupus erythematosus(CLE) as demonstrated by immunohistochemistry, 2009
McCann L; Ingham E; Jin Z; Fisher J Influence of the meniscus on friction and degradation of cartilage in the natural knee joint OSTEOARTHRITIS AND CARTILAGE 17 995-1000, 2009
DOI:10.1016/j.joca.2009.02.012
Leslie IJ; Williams S; Brown C; Anderson J; Isaac G; Hatto P; Ingham E; Fisher J Surface Engineering: A Low Wearing Solution for Metal-On-Metal Hip Surface Replacements JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 90B 558-565, 2009
DOI:10.1002/jbm.b.31317
Leslie IJ; Williams S; Isaac G; Ingham E; Fisher J High Cup Angle and Microseparation Increase the Wear of Hip Surface Replacements CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 467 2259-2265, 2009
DOI:10.1007/s11999-009-0830-x
Wang L; Wilshaw SP; Korossis S; Fisher J; Jin Z; Ingham E Factors Influencing the Oxygen Consumption Rate of Aortic Valve Interstitial Cells: Application to Tissue Engineering., 2009
DOI:10.1089/ten.tea.2008.0415
Katta J; Jin Z; Ingham E; Fisher J Effect of nominal stress on the long term friction, deformation and wear of native and glycosaminoglycan deficient articular cartilage OSTEOARTHRITIS AND CARTILAGE 17 662-668, 2009
DOI:10.1016/j.joca.2008.10.008
da Costa FDA; Santos LR; Collatusso C; Matsuda CN; Lopes SAV; Cauduro S; Roderjan JG; Ingham E Thirteen Years' Experience with the Ross Operation JOURNAL OF HEART VALVE DISEASE 18 84-94, 2009
Wang L; Korossis S; Ingham E; Fisher J; Jin Z Computational Simulation of Oxygen Diffusion in Aortic Valve Leaflet for Tissue Engineering Applications JOURNAL OF HEART VALVE DISEASE 17 700-709, 2008
Stapleton TW; Ingram J; Katta J; Knight R; Korossis S; Fisher J; Ingham E Development and characterization of an acellular porcine medial meniscus for use in tissue engineering TISSUE ENGINEERING PART A 14 505-518, 2008
DOI:10.1089/tea.2007.0233
Stapleton TW; Ingram J; Fisher J; Ingham E Biocompatibility of an acellular porcine meniscal scaffold, 2008
Wang L; Wilshaw S; Korossis S; Fisher J; Jin ZM; Ingham E Measurement of oxygen consumption rate for aortic valve interstitial cells (VICs): Application to tissue engineering, 2008
Katta J; Jin Z; Ingham E; Fisher J Biotribology of articular cartilage-A review of the recent advances MEDICAL ENGINEERING&PHYSICS 30 1349-1363, 2008
DOI:10.1016/j.medengphy.2008.09.004
Holland DB; Bojar RA; Jeremy AHT; Ingham E; Holland KT Microbial colonization of an in vitro model of a tissue engineered human skin equivalent - a novel approach FEMS MICROBIOLOGY LETTERS 279 110-115, 2008
DOI:10.1111/j.1574-6968.2007.01021.x
Williams S; Leslie I; Isaac G; Jin Z; Ingham E; Fisher J Tribology and wear of metal-on-metal hip prostheses: Influence of cup angle and head position JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME 90A 111-117, 2008
DOI:10.2106/JBJS.H.00485
Wilshaw SP; Aggeli A; Fisher J; Ingham E The biocompatibility and immunogenicity of self-assembling peptides for use in tissue engineering and regenerative applications, 2008
Wilshaw S; Kearney J; Fisher J; Ingham E Biocompatibility and potential of acellular human amniotic membrane to support the attachment and proliferation of allogeneic cells TISSUE ENGINEERING PART A 14 463-472, 2008
DOI:10.1089/tea.2007.0145
Derham C; Yow H; Ingram J; Fisher J; Ingham E; Korrosis SA; Homer-Vanniasinkam S Tissue Engineering Small-Diameter Vascular Grafts: Preparation of a Biocompatible Porcine Ureteric Scaffold TISSUE ENGINEERING PART A 14 1871-1882, 2008
DOI:10.1089/ten.tea.2007.0103
McCann L; Udofia I; Graindorge S; Ingham E; Jin Z; Fisher J Tribological testing of articular cartilage of the medial compartment of the knee using a friction simulator TRIBOLOGY INTERNATIONAL 41 1126-1133, 2008
DOI:10.1016/j.triboint.2008.03.012
Derham C; Khan T; Ingram J; Ingham E; Homer-Vanniasinkam S Biocompatibility of a decellularised ureteric scaffold for tissue engineering small diameter vessels, 2008
Katta J; Stapleton T; Ingham E; Jin ZM; Fisher J The effect of glycosaminoglycan depletion on the friction and deformation of articular cartilage PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 222 1-11, 2008
DOI:10.1243/09544119JEIM325
Knight RL; Wilcox HE; Korossis SA; Fisher J; Ingham E The use of acellular matrices for the tissue engineering of cardiac valves PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 222 129-143, 2008
DOI:10.1243/09544119JEIM230
Miller K; O'Neill AJ; Wilcox MH; Ingham E; Chopra I Delayed development of linezolid resistance in Staphylococcus aureus following exposure to low levels of antimicrobial agents ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 52 1940-1944, 2008
DOI:10.1128/AAC.01302-07
Papageorgiou I; Shadrick V; Davis S; Hails L; Schins R; Newson R; Fisher J; Ingham E; Case CP Macrophages detoxify the genotoxic and cytotoxic effects of surgical cobalt chrome alloy particles but not quartz particles on human cells in vitro MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS 643 11-19, 2008
DOI:10.1016/j.mrfmmm.2008.05.004
Hidalgo-Bastida LA; Ingram JH; Majani R; Falcone FH; Buttery LD; Rose FRAJ; Ingham E; Claycomb WC; Shakesheff KM Biomechanical stimulation of Hl-1 cardiomyocytes cultured in poly-(1,8-octanediol-co-citricacid) [Poc] scaffolds, 2008
Leslie I; Williams S; Brown C; Isaac G; Jin Z; Ingham E; Fisher J Effect of bearing size on the long-term wear, wear debris, and ion levels of large diameter metal-on-metal hip replacements - An in vitro study JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 87B 163-172, 2008
DOI:10.1002/jbm.b.31087
Kyle S; Riley JM; Aggeli A; Ingham E; McPherson MJ Self-assembling peptides for scaffolds in regenerative medicine: Production using recombinant DNA technology, 2008
Galvin A; Brockett C; Williams S; Hatto P; Burton A; Isaac G; Stone M; Ingham E; Fisher J Comparison of wear of ultra-high molecular weight polyethylene acetabular cups against surface-engineered femoral heads PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 222 1073-1080, 2008
DOI:10.1243/09544119JEIM407
Thomas DS; Ingham E; Bojar RA; Holland KT In vitro modulation of human keratinocyte pro- and anti-inflammatory cytokine production by the capsule of Malassezia species FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY 54 203-214, 2008
DOI:10.1111/j.1574-695X.2008.00468.x
Richards L; Brown C; Stone MH; Fisher J; Ingham E; Tipper JL Identification of nanometre-sized ultra-high molecular weight polyethylene wear particles in samples retrieved in vivo JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 90B 1106-1113, 2008
DOI:10.1302/0301-620X.90B8.20737
Durham E; Russell SJ; Ingham E Scaffold design for tissue engineering the anterior cruciate ligament European Cells and Materials 16 8-8, 2008
Wilshaw SP; Aggeli A; Fisher J; Ingham E In vivo assessment of the immunogenicity of self-assembling peptides for use in regenerative applications European Cells and Materials 16 97-97, 2008
Hidalgo-Bastida LA; Ingram JH; Majani R; Falcone FH; White LJ; Ingham E; Claycomb WC; Buttery LD; Rose FRAJ; Shakesheff KM Mechanical stimulation of HL-1 cardiomyocytes cultured in poly-(1,8-octanediol-co-citric acid) [POC] scaffolds European Cells and Materials 16 60-60, 2008
Kyle S; Aggeli A; McPherson MJ; Ingham E The self-assembling peptide, P 11-4 as a scaffold for use in regenerative medicine European Cells and Materials 16 70-70, 2008
Williams S; Schepers A; Isaac G; Hardaker C; Ingham E; Jagt DVD; Breckon A; Fisher J Ceramic-on-metal hip arthroplasties: A comparative in vitro and in vivo study Clinical Orthopaedics and Related Research 23-32, 2007
Oliver R; Yee G; Yu Y; Matthews JB; Ingham E; Walsh WR Fracture healing in the presence of polyethylene wear debris and oestrogen deficiency Key Engineering Materials 353-358 831-834, 2007
Mirsadraee S; Wilcox HE; Watterson KG; Kearney JN; Hunt J; Fisher J; Ingham E Biocompatibility of acellular human pericardium JOURNAL OF SURGICAL RESEARCH 143 407-414, 2007
DOI:10.1016/j.jss.2007.01.026
Katta J; Pawaskar SS; Jin ZM; Ingham E; Fisher J Effect of load variation on the friction properties of articular cartilage, 2007
Jennings LM; Bell CJ; Ingham E; Komistek RD; Stone MH; Fisher J The influence of femoral condylar lift-off on the wear of artificial knee joints PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 221 305-314, 2007
DOI:10.1243/09544119JEIM215
Oswal D; Korossis S; Mirsadraee S; Wilcox H; Watterson K; Fisher J; Ingham E Biomechanical characterization of decellularized and cross-linked bovine pericardium JOURNAL OF HEART VALVE DISEASE 16 165-174, 2007
Brown C; Williams S; Tipper JL; Fisher J; Ingham E Characterisation of wear particles produced by metal on metal and ceramic on metal hip prostheses under standard and microseparation simulation JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 18 819-827, 2007
DOI:10.1007/s10856-006-0015-z
Bolland F; Korossis S; Wilshaw S; Ingham E; Fisher J; Kearney JN; Southgate J Development and characterisation of a full-thickness acellular porcine bladder matrix for tissue engineering BIOMATERIALS 28 1061-1070, 2007
DOI:10.1016/j.biomaterials.2006.10.005
Bolland F; Korossis S; Ingham E; Fisher J; Kearney JN; Southgate J Functional tissue-engineering of the urinary bladder, 2007
Papageorgiou I; Brown C; Schins R; Singh S; Newson R; Davis S; Fisher J; Ingham E; Case CP The effect of nano- and micron-sized particles of cobalt-chromium alloy on human fibroblasts in vitro Biomaterials 28 2946-2958, 2007
Carrick LM; Aggeli A; Boden N; Fisher J; Ingham E; Waigh TA Effect of ionic strength on the self-assembly, morphology and gelation of pH responsive beta-sheet tape-forming peptides TETRAHEDRON 63 7457-7467, 2007
DOI:10.1016/j.tet.2007.05.036
Ingram JH; Korossis S; Howling G; Fisher J; Ingham E The use of ultrasonication to aid recellularization of acellular natural tissue scaffolds for use in anterior cruciate ligament reconstruction TISSUE ENGINEERING 13 1561-1572, 2007
DOI:10.1089/ten.2006.0362
Papageorgiou I; Brown C; Schins R; Singh S; Newson R; Davis S; Fisher J; Ingham E; Case CP The effect of nano- and micron-sized particles of cobalt-chromium alloy on human fibroblasts in vitro BIOMATERIALS 28 2946-2958, 2007
DOI:10.1016/j.biomaterials.2007.02.034
Ingham E Host response to biomaterial implants: Biological activity of prosthetic wear particles, 2007
DOI:10.1016/j.tox.2007.06.017
Galvin AL; Tipper IL; Jennings LM; Stone MH; Jin ZM; Ingham E; Fisher J Wear and biological activity of highly crosslinked polyethylene in the hip under low serum protein concentrations PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 221 1-10, 2007
DOI:10.1243/09544119JEIM99
Katta J; Pawaskar SS; Jin ZM; Ingham E; Fisher J Effect of load variation on the friction properties of articular cartilage PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART J-JOURNAL OF ENGINEERING TRIBOLOGY 221 175-181, 2007
DOI:10.1243/13506501JET240
Wilcox HE; Farrar MD; Cunliffe WJ; Holland KT; Ingham E Resolution of inflammatory acne vulgaris may involve regulation of CD4+ T-cell responses to Propionibacterium acnes BRITISH JOURNAL OF DERMATOLOGY 156 460-465, 2007
DOI:10.1111/j.1365-2133.2006.07631.x
Williams S; Schepers A; Isaac G; Hardaker C; Ingham E; van der Jagt D; Breckon A; Fisher J The 2007 Otto Aufranc Award - Ceramic-on-metal hip arthroplasties - A comparative in vitro and in vivo study CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 23-32, 2007
DOI:10.1097/BLO.0b013e31814da946
Bell CJ; Carrick LM; Katta J; Jin Z; Ingham E; Aggeli A; Boden N; Waigh TA; Fisher J Self-assembling peptides as injectable lubricants for osteoarthritis JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 78A 236-246, 2006
DOI:10.1002/jbm.a.30672
Williams S; Jalali-Vahid D; Brockett C; Jin Z; Stone MH; Ingham E; Fisher J Effect of swing phase load on metal-on-metal hip lubrication, friction and wear JOURNAL OF BIOMECHANICS 39 2274-2281, 2006
DOI:10.1016/j.jbiomech.2005.07.011
Forsey RW; Fisher J; Thompson J; Stone MH; Bell CJ; Ingham E The effect of hyaluronic acid and phospholipid based lubricants on friction within a human cartilage damage model Biomaterials 27 4581-4590, 2006
DOI:10.1016/j.biomaterials.2006.04.018
Jin ZM; Stone M; Ingham E; Fisher J Biotribology CURRENT ORTHOPAEDICS 20 32-40, 2006
DOI:10.1016/j.cuor.2005.09.005
Korossis S; Bolland F; Ingham E; Fisher J; Kearney J; Southgate J Tissue engineering of the urinary bladder: Considering structure-function relationships and the role of mechanotransduction TISSUE ENGINEERING 12 635-644, 2006
DOI:10.1089/ten.2006.12.635
Galvin A; Kang L; Tipper J; Stone M; Ingham E; Jin ZM; Fisher J Wear of crosslinked polyethylene under different tribological conditions JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 17 235-243, 2006
DOI:10.1007/s10856-006-7309-z
Thomas DS; Ingham E; Meldrum H; Holland KT Effects of de-capsulation of Malassezia spp. on the pro-inflammatory cytokine production of normal human keratinocytes, 2006
Hall RM; Brown TD; Fisher J; Ingham E; Mendoza SA; Mayer HM Introduction to lumbar total disc replacement: factors that affect tribological performance PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART J-JOURNAL OF ENGINEERING TRIBOLOGY 220 775-786, 2006
DOI:10.1243/13506501JET187
Tiller JL; Galvin AL; Ingham E; Fisher J Estimation of the osteolytic potential of noncrosslinked and crosslinked polyethylenes and ceramic-on-ceramic total hip prostheses, 2006
Stubbings W; Bostock J; Ingham E; Chopra I Mechanisms of the post-antibiotic effects induced by rifampicin and gentamicin in Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 58 444-448, 2006
DOI:10.1093/jac/dkl225
Edwards SL; Russell SJ; Ingham E; Matthews JB; Mitchell W Nonwoven scaffolds of improved design for the tissue engineering of the anterior cruciate ligament, 2006
Fisher J; Jin Z; Tipper J; Stone M; Ingham E Presidential guest lecture - Tribology of alternative beatings CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 25-34, 2006
DOI:10.1097/01.blo.0000238871.07604.49
Oswal D; Korossis S; Mirsadraee S; Wilcox HE; Watterson KG; Fisher J; Ingham E Biomechanical characterisation of decellularised and cross linked bovine pericardium European Cells and Materials 11 pp.76-, 2006
Graindorge S; Ferrandez W; Ingham E; Jin Z; Twigg P; Fisher J The role of the surface amorphous layer of articular cartilage in joint lubrication PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 220 597-607, 2006
DOI:10.1243/09544119JEIM122
Graindorge S; Ferrandez W; Jin Z; Ingham E; Fisher J The natural synovial joint: a finite element investigation of biphasic surface amorphous layer lubrication under dynamic loading conditions PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART J-JOURNAL OF ENGINEERING TRIBOLOGY 220 671-681, 2006
DOI:10.1243/13506501JET95
Jin Z; Fisher J; Ingham E Biotribology: Material Design, Lubrication and Wear in Artificial Hip Joints In CRC Handbook of Lubrication - Theory and Practice of Tribology: Volume 1 -Application and Maintenance , 2006
Wilshaw S; Kearney JN; Fisher J; Ingham E Production of an acellular amniotic membrane matrix for use in tissue engineering TISSUE ENGINEERING 12 2117-2129, 2006
DOI:10.1089/ten.2006.12.2117
Derham C; Yow H; Ingram J; Ingham E; Homer-Vanniasinkam S Decellularised scaffolds as a potential for vascular tissue engineering of small calibre grafts ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND 88 594-594, 2006
DOI:10.1308/003588406X130723
Mirsadraee S; Wilcox HE; Korossis SA; Kearney JN; Watterson KG; Fisher J; Ingham E Development and characterization of an acellular human pericardial matrix for tissue engineering TISSUE ENGINEERING 12 763-773, 2006
DOI:10.1089/ten.2006.12.763
Jin Z; Williams S; Tipper JL; Ingham E; Fisher J Tribology of hip joints from natural hip joints, cartilage substitution, artificial replacements to cartilage tissue engineering Journal of Biomechanical Science and Engineering 1 69-81, 2006
Tipper JL; Galvin AL; Ingham E; Fisher J Estimation of the osteolytic potential of noncrosslinked and crosslinked polyethylenes and ceramic-on-ceramic total hip prostheses Journal of ASTM International 3 -, 2006
Holland DB; Wright JD; Longshaw CM; Bojar RA; Ingham E; Holland KT Lipases of staphylococcal epidermidis - Are they important for skin colonisation?, 2006
Bell CJ; Ingham E; Fisher J Influence of hyaluronic acid on the time-dependent friction response of articular cartilage under different conditions PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 220 23-31, 2006
DOI:10.1243/095441105X69060
Tipper JL; Galvin AL; Williams S; McEwen HMJ; Stone MH; Ingham E; Fisher J Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A 78A 473-480, 2006
DOI:10.1002/jbm.a.30824
Jin Z; Tipper JL; Stone MH; Ingham E; Fisher J Hip Joints, Artificial In Encyclopedia of Medical Devices and Instrumentation , 2006
Fisher J; McEwen H; Tipper J; Jennings L; Farrar R; Stone M; Ingham E Wear-simulation analysis of rotating-platform mobile-bearing knees ORTHOPEDICS 29 S36-S41, 2006
Jin ZM; Stone M; Ingham E; Fisher J (v) Biotribology Current Orthopaedics 20 32-40, 2006
Fisher J; Jin Z; Tipper J; Stone M; Ingham E Tribology of alternative bearings. Clinical orthopaedics and related research 453 25-34, 2006
Yow KH; Ingram J; Korossis SA; Ingham E; Homer-Vanniasinkam S Tissue engineering of vascular conduits BRITISH JOURNAL OF SURGERY 93 652-661, 2006
DOI:10.1002/bjs.5343
Wang FC; Galvin AL; Jin ZM; Ingham E; Fisher J An integrated experimental and theoretical contact mechanics study of uhmwpe hip implants tested in a hip simulator Proceedings of the World Tribology Congress III - 2005 311-312, 2005
Williams S; Jin ZM; Stone MH; Ingham E; Fisher J The effect of different lubrication regimes and lubricants on the friction hard-on-hard total hip replacements Proceedings of the World Tribology Congress III - 2005 625-626, 2005
Tipper JL; Ingham E; Jin ZM; Fisher J (iv) The science of metal-on-metal articulation Current Orthopaedics 19 280-287, 2005
Galvin AL; Tipper JL; Ingham E; Fisher J Nanometre size wear debris generated from crosslinked and non-crosslinked ultra high molecular weight polyethylene in artificial joints WEAR 259 977-983, 2005
DOI:10.1016/j.wear.2005.02.035
Graindorge S; Ferrandez W; Jin ZM; Ingham E; Grant C; Twigg P; Fisher J Biphasic surface amorphous layer lubrication of articular cartilage MEDICAL ENGINEERING&PHYSICS 27 836-844, 2005
DOI:10.1016/j.medengphy.2005.05.001
Wilcox HE; Korossis SA; Booth C; Watterson KG; Kearney JN; Fisher J; Ingham E Biocompatibility and recellularization potential of an acellular porcine heart valve matrix Journal of Heart Valve Disease 14 228-236, 2005
Korossis S; Bolland F; Kearney JN; Fisher J; Ingham E Bioreactors in tissue engineering In Topics in Tissue Engineering , 2005
Korossis SA; Wilcox HE; Watterson KG; Kearney JN; Ingham E; Fisher J In-vitro assessment of the functional performance of the decellularized intact porcine aortic root JOURNAL OF HEART VALVE DISEASE 14 408-421, 2005
Knight RL; Booth C; Wilcox HE; Fisher J; Ingham E Tissue engineering of cardiac valves: Re-seeding of acellular porcine aortic valve matrices with human mesenchymal progenitor cells JOURNAL OF HEART VALVE DISEASE 14 806-813, 2005
Mirsadraee S; Wilcox HE; Korossis SA; Kearney JN; Fisher J; Ingham E Tissue engineered human pericardium: a potential decellularised matrix for bladder wall augmentation BJU INTERNATIONAL 95 66-66, 2005
Clarke MT; Darrah C; Stewart T; Ingham E; Fisher J; Nolan JF Long-term clinical, radiological and histopathological follow-up of a well-fixed McKee-Farrar metal-on-metal total hip arthroplasty JOURNAL OF ARTHROPLASTY 20 542-546, 2005
DOI:10.1016/j.arth.2004.09.063
Tipper JL; Ingham E; Jin Z; Fisher J The science of metal-on-metal articulation Current Orthopaedics 19 280-287, 2005
DOI:10.1016/j.cuor.2005.08.002
Ingram JH; Kowalski R; Fisher J; Ingham E The osteolytic response of macrophages to challenge with particles of simplex P, endurance, palacos R, and vertebroplastic bone cement particles in vitro JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 75B 210-220, 2005
DOI:10.1002/jbm.b.30308
Tipper JL; Ingham E; Jin ZM; Fisher J The science of metal-on-metal articulation CURRENT ORTHOPAEDICS 19 280-287, 2005
DOI:10.1016/j.cuor.2005.08.002
Williams S; Jin Z; Stone MH; Ingham E; Fisher J The effect of different lubrication on regimes and lubricants on the friction hard-on-hard total hip replacements, 2005
Fisher J; Firkins P; Tipper JL; Farrar R; Ingham E Wear of a Novel Ceramic on Metal Bearings for Hip Prosthesis, 2005
DOI:10.1007/3-7985-1540-9_30
Carrick L; Tassieri M; Waigh TA; Aggeli A; Boden N; Bell C; Fisher J; Ingham E; Evans RML The internal dynamic modes of charged self-assembled peptide fibrils LANGMUIR 21 3733-3737, 2005
DOI:10.1021/la046802f
Fisher J; Galvin A; Tipper J; Stewart T; Stone M; Ingham E Comparison of the Functional Biological Activity and Osteolytic Potential of Ceramic on Ceramic and Cross Linked Polyethylene Bearings in the Hip, 2005
DOI:10.1007/3-7985-1540-9_3
Ingham E; Fisher J The role of macrophages in osteolysis of total joint replacement Biomaterials 26 1271-1286, 2005
Wilcox HE; Korossis SA; Booth C; Watterson KG; Kearney JN; Fisher J; Ingham E Biocompatibility and recellularization potential of an acellular porcine heart valve matrix JOURNAL OF HEART VALVE DISEASE 14 228-237, 2005
Galvin AL; Williams S; Hatto P; Thompson J; Isaac G; Stone M; Ingham E; Fisher J Comparison of wear of ultra high molecular weight polyethylene acetabular cups against alumina ceramic and chromium nitride coated femoral heads WEAR 259 972-976, 2005
DOI:10.1016/j.wear.2005.02.016
Korossis S; Wilcox HE; Watterson KG; Kearney JN; Ingham E; Fisher J In-Vitro Assessment of the Functional Performance of the Decellularized Intact Porcine Aortic Root The Journal of Heart Valve Disease 14 408-422, 2005
Ingham E; Fisher J The role of macrophages in osteolysis of total joint replacement BIOMATERIALS 26 1271-1286, 2005
DOI:10.1016/j.biomaterials.2004.04.035
Wilcox HE; Korossis SA; Booth C; Watterson KG; Kearney JN; Fisher J; Ingham E Biocompatibility and recellularization potential of an acellular porcine heart valve matrix. J Heart Valve Dis 14 228-236, 2005
Stubbings W; Bostock J; Ingham E; Chopra I Deletion of the multiple-drug efflux pump AcrAB in Escherichia coli prolongs the postantibiotic effect ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 49 1206-1208, 2005
DOI:10.1128/AAC.49.3.1206-1208.2005
Crallan RA; Ingham E; Routledge MN Wavelength dependent responses of primary human keratinocytes to combined treatment with benzo[a]pyrene and UV light MUTAGENESIS 20 305-310, 2005
DOI:10.1093/mutage/gei042
Galvin AL; Ingham E; Fisher J Wear of crosslinked UHMWPE in a hip joint simulator, 2005
Wang F; Galvin AL; Jin Z; Ingham E; Fisher J An integrated experimental and theoretical contact mechanics study of UHMWPE hip implants tested in a hip simulator, 2005
Howling GI; Ingham E; Sakoda H; Stewart TD; Fisher J; Antonarulrajah A; Appleyard S; Rand B Carbon-carbon composite bearing materials in hip arthroplasty: analysis of wear and biological response to wear debris JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 15 91-98, 2004
DOI:10.1023/B:JMSM.0000010102.26218.d1
Stubbings WJ; Bostock JM; Ingham E; Chopra I Assessment of a microplate method for determining the post-antibiotic effect in Staphylococcus aureus and Escherichia coli JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 54 139-143, 2004
DOI:10.1093/jac/dkh275
Crallan R; Ingham E; Routledge MN Exposure of primary human keratinocytes to a binary mixture of carcinogens MUTAGENESIS 19 514-514, 2004
Makris G; Wright JD; Ingham E; Holland KT The hyaluronate lyase of Staphylococcus aureus - a virulence factor? MICROBIOLOGY-SGM 150 2005-2013, 2004
DOI:10.1099/mic.0.26942-0
Williams S; Stewart TD; Ingham E; Stone MH; Fisher J Metal-on-metal bearing wear with different swing phase loads JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 70B 233-239, 2004
DOI:10.1002/jbm.b.30052
Graham GM; Farrar MD; Cruse-Sawyer JE; Holland KT; Ingham E Proinflammatory cytokine production by human keratinocytes stimulated with Propionibacterium acnes and P-acnes GroEL BRITISH JOURNAL OF DERMATOLOGY 150 421-428, 2004
DOI:10.1046/j.1365-2133.2004.05762.x
Hurdle JG; O'Neill AJ; Ingham E; Fishwick C; Chopra I Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modeling techniques ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 48 4366-4376, 2004
DOI:10.1128/AAC.48.11.4366-4376.2004
Farrar MD; Ingham E Acne: Inflammation CLINICS IN DERMATOLOGY 22 380-384, 2004
DOI:10.1016/j.clindermatol.2004.03.006
Edwards SL; Mitchell W; Matthews JB; Ingham E; Russell SJ Design of nonwoven scaffold structures for tissue engineering of the anterior cruciate ligament Autex Research Journal 4 86-94, 2004
Fisher J; Nevelos J; Stewart TD; Tipper JL; Ingham E Long term wear of ceramic on ceramic hips, 2004
Jappe U; Henwood JA; Ingham E; Holland KT Does Propionibacterium acnes have superantigenic properties? Clinical and Experimental Dermatology 29 1-6, 2004
DOI:10.1111/j.1365-2230.2004.01438.x
Bell CJ; Carrick LM; Ingham E; Aggeli A; Boden N; Waigh TA; Fisher J; medimond Self-assembling peptide nanomaterials as injectable lubricants for osteoarthritis, 2004
Williams S; Isaac G; Hatto P; Stone MH; Ingham E; Fisher J Comparative wear under different conditions of surface-engineered metal-on-metal bearings for total hip arthroplasty JOURNAL OF ARTHROPLASTY 19 112-117, 2004
DOI:10.1016/j.arth.2004.09.014
Lithgow JK; Ingham E; Foster SJ Role of the hprT-ftsH locus in Staphylococcus aureus MICROBIOLOGY-SGM 150 373-381, 2004
DOI:10.1099/mic.0.26674-0
Horsburgh MJ; Wiltshire MD; Crossley H; Ingham E; Foster SJ PheP, a putative amino acid permease of Staphylococcus aureus, contributes to survival in vivo and during starvation INFECTION AND IMMUNITY 72 3073-3076, 2004
DOI:10.1128/IAI.72.5.3073-3076.2004
Fisher J; McEwen HMJ; Barnett PI; Bell C; Stone MH; Ingham E Influences of sterilising techniques on polyethylene wear KNEE 11 173-176, 2004
DOI:10.1016/j.knee.2003.10.002
Fisher J; Hu XQ; Stewart TD; Williams S; Tipper JL; Ingham E; Stone MH; Davies C; Hatto P; Bolton J; Riley M; Hardaker C; Isaac GH; Berry G Wear of surface engineered metal-on-metal hip prostheses JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 15 225-235, 2004
DOI:10.1023/B:JMSM.0000015482.24542.76
Ingram JH; Stone M; Fisher J; Ingham E The influence of molecular weight, crosslinking and counterface roughness on TNF-alpha production by macrophages in response to ultra high molecular weight polyethylene particles BIOMATERIALS 25 3511-3522, 2004
DOI:10.1016/j.biomaterials.2003.10.054
Jappe U; Boit R; Farrar MD; Ingham E; Sandoe J; Holland KT Evidence for diversity within Propionibacterium acnes: a comparison of the T-cell stimulatory activity of isolates from inflammatory acne, endocarditis and the laboratory JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 18 450-454, 2004
DOI:10.1111/j.1468-3083.2004.00950.x
Fisher J; McEwen HMJ; Tipper JL; Galvin AL; Ingram J; Kamali A; Stone MH; Ingham E Wear, debris, and biologic activity of cross-linked polyethylene in the knee - Benefits and potential concerns CLINICAL ORTHOPAEDICS AND RELATED RESEARCH 114-119, 2004
DOI:10.1097/01.blo.0000148783.20469.4c
Jappe U; Holland KT; Ingham E; Huebsch-Mueller C; Farrar MD The Propionibacterium acnes mitogen is not a bacterial heat shock protein, 2004
Wilcox HE; Korossis SA; Booth C; Watterson KG; Kearney JN; Fisher J; Ingham E Tissue engineering a living heart valve: Biological and biomechanical assessment of an acellular porcine valve matrix Transactions - 7th World Biomaterials Congress 438-438, 2004
Galvin AL; Tipper JL; McEwen HMJ; Williams S; Stone MH; Ingham E; Fisher J Nanometre sized polyethylene wear debris in hip and knee prostheses Transactions - 7th World Biomaterials Congress 345-345, 2004
Fisher J; Ingham E Wear, debris, functional biocompatibility and osteolytic potential in artificial hip joints Transactions - 7th World Biomaterials Congress 23-23, 2004
Galvin AL; Endo MM; Tipper JL; Ingham E; Fisher J Functional biological activity of non-crosslinked and crosslinked UHMWPE hip joint prostheses Transactions - 7th World Biomaterials Congress 145-145, 2004
Williams S; Stone MH; Ingham E; Fisher J Metal-on-metal hip replacements; Effect of swing phase load on wear, wear particles and metal ion release Transactions - 7th World Biomaterials Congress 1127-1127, 2004
Fisher J; Stewart TD; Tipper JL; Hatton A; Ingham E Wear, debris and functional biocompatability of third and fourth generation ceramic on ceramic bearing couples Transactions - 7th World Biomaterials Congress 223-223, 2004
Carrick LM; Bell CJ; Ingham E; Aggeli A; Boden N; Waigh TA; Fisher J Self-assembling peptide nanomaterials as injectable lubricants for osteoarthritic joints Transactions - 7th World Biomaterials Congress 618-618, 2004
Jennings LM; Bell CJ; Ingham E; Komistek R; Stone MH; Fisher J The influence of femoral condylar lift off on the wear of artificial knee joints Transactions - 7th World Biomaterials Congress 535-535, 2004
Williams S; Hu XQ; Hatto P; Isaac G; Stone MH; Ingham E; Fisher J Surface engineered metal-on-metal bearings for hip replacement Transactions - 7th World Biomaterials Congress 85-85, 2004
Ingram JH; Korosis S; Fisher J; Ingham E Decellularisation and recellularisation of porcine patella tendon for ACL reconstruction Transactions - 7th World Biomaterials Congress 1007-1007, 2004
Korossis S; Wilcox H; Watterson K; Kearney J; Ingham E; Fisher J Hydrodynamic characterisation of the decellularised intact porcine aortic valve Proceedings of the IASTED International Conference on Biomechanics 288-296, 2003
Ingham E; Fisher J; Stone MH Wear of historical polyethylenes in hip prostheses. Biomedical success and a biological failure HIP International 13 1 S17-S27, 2003
Fisher J; Ingham E; Stone MH Alternative bearing couples in total hip replacements: Solutions for young patients HIP International 13 1 S31-S35, 2003
Ingham E; Fisher J; Stone MH Wear of historical polyethylenes in hip prostheses. Biomechanical success and a biological failure Hip International 13 17-27, 2003
Stewart TD; Tipper JL; Insley GM; Streicher RM; Ingham E; Fisher J Wear of alumina matrix composite ceramics for hip prostheses, 2003
Fisher J; Ingham E; Stone MH Alternate bearing couples in total hip replacements: Solutions for young patients Hip International 13 31-35, 2003
Stewart TD; Tipper JL; Insley G; Streicher RM; Ingham E; Fisher J Severe wear and fracture of zirconia heads against alumina inserts in hip simulator studies with microseparation JOURNAL OF ARTHROPLASTY 18 726-734, 2003
DOI:10.1054/S0883-5403(03)00204-3
Jappe U; Henwood JA; Ingham E; Holland KT T-cell stimulatory activity of Propionibacterium acnes Archives of Dermatological Research 294 pp.469-, 2003
Karavolos MH; Horsburgh MJ; Ingham E; Foster SJ Role and regulation of the superoxide dismutases of Staphylococcus aureus MICROBIOLOGY-SGM 149 2749-2758, 2003
DOI:10.1099/mic.0.26353-0
Howling GI; Sakoda H; Antonarulrajah A; Marrs H; Stewart TD; Appleyard S; Rand B; Fisher J; Ingham E Biological response to wear debris generated in carbon based composites as potential bearing surfaces for artificial hip joints JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 67B 758-764, 2003
DOI:10.1002/jbm.b.10068
Percival RS; Marsh PD; Devine DA; Bonass WA; Matthews JB; Ingham E Effect of haemin, ph and temperature on porphyromonas gingivalis growth and tnf-a induction., 2003
Forsey RW; Ingham E; Fisher J; Bell C; Thompson J; Stone MH A comparison study of the effect of novel hyaluronic acid (HA) based therapeutic lubricants on friction levels of osteoarthritic damaged human cartilage, 2003
Mitchell W; Matthews JB; Stone MH; Fisher J; Ingham E Comparison of the response of human peripheral blood mononuclear cells to challenge with particles of three bone cements in vitro BIOMATERIALS 24 737-748, 2003
DOI:10.1016/S0142-9612(02)00405-2
Korossis S; Wilcox HE; Booth C; Watterson KG; Kearney JN; Ingham E; Fisher J Biomechanical and hydrodynamic characterisation of decellularised intact porcine aortic valves for tissue engineering Tissue Engineering 9 pp.838-, 2003
Stewert TD; Williams S; Tipper JL; Ingham E; Stone MH; Fisher J Advances in simulator testing of orthopaedic joint prostheses, 2003
Stewart TD; Tipper JL; Insley G; Streicher RM; Ingham E; Fisher J Long-term wear of ceramic matrix composite materials for hip prostheses under severe swing phase microseparation JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS 66B 567-573, 2003
DOI:10.1002/jbm.b.10035
Lomas RJ; Cruse-Sawyer JE; Simpson C; Ingham E; Bojar R; Kearney JN Assessment of the biological properties of human split skin allografts disinfected with peracetic acid and preserved in glycerol BURNS 29 515-525, 2003
DOI:10.1016/S0305-4179(03)00137-2
Williams S; Tipper JL; Ingham E; Stone MH; Fisher J In vitro analysis of the wear, wear debris and biological activity of surface-engineered coatings for use in metal-on-metal total hip replacements Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 217 155-163, 2003
Williams S; Tipper JL; Hu XQ; Stone MH; Ingham E; Isaac GH; Hatto P; Fisher J The influence of swing phase loading on wear of metal-on-metal and Crn surface modified total hip replacements, 2003
Tipper JL; Matthews JB; Ingham E; Stewart TD; Fisher J; Stone MH Wear and functional biological activity of wear debris generated from UHMWPE-on-Zirconia ceramic, metal-on-metal, and alumina ceramic-on-ceramic hip prostheses during hip simulator testing, 2003
Shardlow DL; Stone MH; Ingham E; Fisher J Cement particles containing radio-opacifiers stimulate pro-osteolytic cytokine production from a human monocytic cell line JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 85B 900-905, 2003
DOI:10.1302/0301-620X.85B6.12813
Germain MA; Hatton A; Williams S; Matthews JB; Stone MH; Fisher J; Ingham E Comparison of the cytotoxicity of clinically relevant cobalt-chromium and alumina ceramic wear particles in vitro BIOMATERIALS 24 469-479, 2003
DOI:10.1016/S0142-9612(02)00360-5
Hatton A; Nevelos JE; Matthews JB; Fisher J; Ingham E Effects of clinically relevant alumina ceramic wear particles on TNF-alpha production by human peripheral blood mononuclear phagocytes BIOMATERIALS 24 1193-1204, 2003
DOI:10.1016/S0142-9612(02)00510-0
Fisher J; Hu XQ; Williams S; Tipper JL; Ingham E; Stone MH; Hatto P; Berry G; Hardaker C; Isaac G New bearing surfaces: What does the future hold? Seminars in Arthroplasty 14 131-139, 2003
Williams S; Butterfield M; Stewart T; Ingham E; Stone M; Fisher J Wear and deformation of ceramic-on-polyethylene total hip replacements with joint laxity and swing phase microseparation PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 217 147-153, 2003
DOI:10.1243/09544110360579367
Graindorge S; Jin Z; Fisher J; Twigg P; Grant C; Ingham E; Mitchell W Biphasic amorpohous surface layer lubrication of articular cartilage - dynamic loading response, 2003
Fisher J; Stone MH; Ingham E Wear of ultra high molecular weight polyethylene. UHMWPE for arthroplasty : past, present and future, 2003
Booth C; Korossis SA; Wilcox HE; Watterson KG; Kearney JN; Fisher J; Ingham E Tissue engineering of cardiac valve prostheses I: Development and histological characterization of an acellular porcine scaffold JOURNAL OF HEART VALVE DISEASE 11 457-462, 2002
Stewart TD; Tipper JL; Stone MH; Ingham E; Fisher J Wear of polyethylene against scratched metallic femoral heads in hip prostheses In Bioceramics in Joint Arthroplasty , 2002
Korossis SA; Booth C; Wilcox HE; Watterson KG; Kearney JN; Fisher J; Ingham E Tissue engineering of cardiac valve prostheses II: Biomechanical characterization of decellularized porcine aortic heart valves JOURNAL OF HEART VALVE DISEASE 11 463-471, 2002
Keig PM; Ingham E; Vandamme PAR; Kerr KG Differential invasion of respiratory epithelial cells by members of the Burkholderia cepacia complex, 2002
DOI:10.1046/j.1469-0691.2002.00356.x
Boit R; Ingham E; Petzoldt D; Holland KT; Jappe U Propionibacterium acnes and T cell stimulation: A comparison between the laboratory strain and clinical isolates Journal of Investigative Dermatology 119 pp.620-, 2002
Endo M; Tipper JL; Barton DC; Stone MH; Ingham E; Fisher J Comparison of wear, wear debris and functional biological activity of moderately crosslinked and non-crosslinked polyethylenes in hip prostheses PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 216 111-122, 2002
DOI:10.1243/0954411021536333
Horsburgh MJ; Wharton SJ; Cox AG; Ingham E; Peacock S; Foster SJ MntR modulates expression of the PerR regulon and superoxide resistance in Staphylococcus aureus through control of manganese uptake MOLECULAR MICROBIOLOGY 44 1269-1286, 2002
DOI:10.1046/j.1365-2958.2002.02944.x
Fisher J; Hu XQ; Tipper JL; Stewart TD; Williams S; Stone MH; Davies C; Hatto P; Bolton J; Riley M; Hardaker C; Isaac GH; Berry G; Ingham E An in vitro study of the reduction in wear of metal-on-metal hip prostheses using surface-engineered femoral heads PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 216 219-230, 2002
DOI:10.1243/09544110260138709
Bell J; Tipper JL; Ingham E; Stone MH; Wroblewski BM; Fisher J Quantitative analysis of UHMWPE wear debris isolated from the periprosthetic femoral tissues from a series of Charnley total hip arthroplasties BIO-MEDICAL MATERIALS AND ENGINEERING 12 189-201, 2002
Jappe U; Ingham E; Henwood J; Holland KT Propionibacterium acnes and inflammation in acne: P-acnes has T-cell mitogenic activity BRITISH JOURNAL OF DERMATOLOGY 146 202-209, 2002
DOI:10.1046/j.1365-2133.2002.04602.x
Hatton A; Nevelos JE; Nevelos AA; Banks RE; Fisher J; Ingham E Alumina-alumina artificial hip joints. Part I: a histological analysis and characterisation of wear debris by laser capture microdissection of tissues retrieved at revision BIOMATERIALS 23 3429-3440, 2002
DOI:10.1016/S0142-9612(02)00047-9
Barnett PI; McEwen HMJ; Auger DD; Stone MH; Ingham E; Fisher J Investigation of wear of knee prostheses in a new displacement/force-controlled simulator PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 216 51-61, 2002
DOI:10.1243/0954411021536289
Boit R; Ingham E; Petzoldt D; Holland K; Jappe U Propionibacterium acnes and T cell stimulation: A comparison between the laboratory strain and clinical isolates JOURNAL OF INVESTIGATIVE DERMATOLOGY 119 311-311, 2002
Ingram J; Matthews JB; Tipper J; Stone M; Fisher J; Ingham E Comparison of the biological activity of grade GUR 1120 and GUR 415HP UHMWPE wear debris BIO-MEDICAL MATERIALS AND ENGINEERING 12 177-188, 2002
Fisher J; Ingham E; Booth C Decellularisation of tissue implant material, 2002
Tipper JL; Hatton A; Nevelos JE; Ingham E; Doyle C; Streicher R; Nevelos AB; Fisher J Alumina-alumina artificial hip joints. Part II: Characterisation of the wear debris from in vitro hip joint simulations BIOMATERIALS 23 3441-3448, 2002
DOI:10.1016/S0142-9612(02)00048-0
Hatton A; Nevelos JE; Nevelos AA; Banks RE; Fisher J; Ingham E Alumina-alumina artificial hip joints. Part I: A histological analysis and characterisation of wear debris by laser capture microdissection of tissues retrieved at revision Biomaterials 23 3429-3440, 2002
Boit R; Bojar R; Ingham E; Holland KT; Petzoldt D; Jappe U Differences between Propionibacterium acnes strains for T-cell stimulation JOURNAL OF INVESTIGATIVE DERMATOLOGY 117 803-803, 2001
McGrath LR; Shardlow DL; Ingham E; Andrews M; Ivory J; Stone MH; Fisher J A retrieval study of Capital hip prostheses with titanium alloy femoral stems JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 83B 1195-1201, 2001
DOI:10.1302/0301-620X.83B8.9874
Fisher J; Stone MH; Tipper JL; Ingham E Wear debris generation with metal-on-polyethylene, metal-on-metal and ceramic-on-ceramic hip prostheses. How good are our in vitro hip joint simulation methods?, 2001
Matthews JB; Green TR; Stone MH; Wroblewski BM; Fisher J; Ingham E Comparison of the response of three human monocytic cell lines to challenge with polyethylene particles of known size and dose JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 12 249-258, 2001
DOI:10.1023/A:1008967200706
Stewart T; Tipper J; Streicher R; Ingham E; Fisher J Long-term wear of HIPed alumina on alumina bearings for THR under microseparation conditions JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 12 1053-1056, 2001
DOI:10.1023/A:1012802308636
Lomas RJ; Gillan HL; Matthews JB; Ingham E; Kearney JN An evaluation of the capacity of differently prepared demineralised bone matrices (DBM) and toxic residuals of ethylene oxide (EtOx) to provoke an inflammatory response in vitro BIOMATERIALS 22 913-921, 2001
DOI:10.1016/S0142-9612(00)00255-6
Horsburgh MJ; Ingham E; Foster SJ In Staphylococcus aureus, Fur is an interactive regulator with PerR, contributes to virulence, and is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis Journal of Bacteriology 183 468-175, 2001
DOI:10.1128/JB.183.2.468-475.2001
Fisher J; Bell J; Barbour PSM; Tipper JL; Matthews JB; Besong AA; Stone MH; Ingham E A novel method for the prediction of functional biological activity of polyethylene wear debris PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 215 127-132, 2001
Horsburgh MJ; Ingham E; Foster SJ In Staphylococcus aureus, Fur is an interactive regulator with PerR, contributes to virulence, and is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis JOURNAL OF BACTERIOLOGY 183 468-475, 2001
DOI:10.1128/JB.183.2.468-475.2001
Tipper JL; Firkins PJ; Besong AA; Barbour PSM; Nevelos J; Stone MH; Ingham E; Fisher J Characterisation of wear debris from UHMWPE on zirconia ceramic, metal-on-metal and alumina ceramic-on-ceramic hip prostheses generated in a physiological anatomical hip joint simulator WEAR 250 120-128, 2001
DOI:10.1016/S0043-1648(01)00653-6
Firkins PJ; Tipper JL; Ingham E; Stone MH; Farrar R; Fisher J Influence of simulator kinematics on the wear of metal-on-metal hip prostheses PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 215 119-121, 2001
DOI:10.1243/0954411011533481
Fisher J; Firkins P; Tipper JL; Ingham E; Stone MH; Farrar R Ceramic-on-metal hip joint prostheses, 2001
Percival RS; Marsh PD; Devine DA; Bonass WA; Matthews JB; Ingham E Effect of various environmental conditions on Porphyromonas gingivalis growth and cytokine production JOURNAL OF DENTAL RESEARCH 80 1148-1148, 2001
Makris G; Ingham E; Holland KT The importance of hyaluronate lyase of Staphylococcus aureus in pathogenicity using a mouse abscess model., 2001
Jappe U; Farrar MD; Ingham E; Holland KT The T-cell mitogen of Propionibacterium acnes is a cell wall component Journal of Investigative Dermatology 117 pp.225-, 2001
Nevelos JE; Prudhommeaux F; Hamadouche M; Doyle C; Ingham E; Meunier A; Nevelos AB; Sedel L; Fisher J Comparative analysis of two different types of alumina-alumina hip prosthesis retrieved for aseptic loosening JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 83B 598-603, 2001
Boit R; Bojar RA; Ingham E; Holland KT; Petzoldt D; Jappe U Differences between Propionibacterium acnes strains for T-cell stimulation Journal of Investigative Dermatology 117 pp.227-, 2001
Endo MM; Barbour PSM; Barton DC; Fisher J; Tipper JL; Ingham E; Stone MH Comparative wear and wear debris under three different counterface conditions of crosslinked and non-crosslinked ultra high molecular weight polyethylene BIO-MEDICAL MATERIALS AND ENGINEERING 11 23-35, 2001
Firkins PJ; Tipper JL; Ingham E; Stone MH; Farrar R; Fisher J A novel low wearing differential hardness, ceramic-on-metal hip joint prosthesis JOURNAL OF BIOMECHANICS 34 1291-1298, 2001
DOI:10.1016/S0021-9290(01)00096-3
Matthews JB; Mitchell W; Stone MH; Fisher J; Ingham E A novel three-dimensional tissue equivalent model to study the combined effects of cyclic mechanical strain and wear particles on the osteolytic potential of primary human macrophages in vitro PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 215 479-486, 2001
DOI:10.1243/0954411011536073
Bell J; Tipper JL; Ingham E; Stone MH; Fisher J The influence of phospholipid concentration in protein-containing lubricants on the wear of ultra-high molecular weight polyethylene in artificial hip joints PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 215 259-263, 2001
DOI:10.1243/0954411011533661
Jappe U; Farrar MD; Ingham E; Holland KT The T-cell mitogen of Propionibacterium acnes is a cell wall component JOURNAL OF INVESTIGATIVE DERMATOLOGY 117 803-803, 2001
Barnett PI; Fisher J; Auger DD; Stone MH; Ingham E Comparison of wear in a total knee replacement under different kinematic conditions JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 12 1039-1042, 2001
DOI:10.1023/A:1012894023657
Firkins PJ; Tipper JL; Saadatzadeh MR; Ingham E; Stone MH; Farrar R; Fisher J Quantitative analysis of wear and wear debris from metal-on-metal hip prostheses tested In a physiological hip joint simulator BIO-MEDICAL MATERIALS AND ENGINEERING 11 143-157, 2001
Saadatzadeh MR; Ashbee HR; Holland KT; Ingham E Production of the mycelial phase of Malassezia in vitro Medical Mycology 39 487-493, 2001
Saadatzadeh MR; Ashbee HR; Cunliffe WJ; Ingham E Cell-mediated immunity to the mycelial phase of Malassezia spp. in patients with pityriasis versicolor and controls BRITISH JOURNAL OF DERMATOLOGY 144 77-84, 2001
DOI:10.1046/j.1365-2133.2001.03955.x
Howling GI; Barnett PI; Tipper JL; Stone MH; Fisher J; Ingham E Quantitative characterization of polyethylene debris isolated from periprosthetic tissue in early failure knee implants and early and late failure Charnley hip implants JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 58 415-420, 2001
DOI:10.1002/jbm.1036
Horsburgh MJ; Clements MO; Crossley H; Ingham E; Foster SJ PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus INFECTION AND IMMUNITY 69 3744-3754, 2001
DOI:10.1128/IAI.69.6.3744-3754.2001
Nevelos JE; Ingham E; Doyle C; Nevelos AB; Fisher J Wear of HIPed and non-HIPed alumina-alumina hip joints under standard and severe simulator testing conditions BIOMATERIALS 22 2191-2197, 2001
DOI:10.1016/S0142-9612(00)00361-6
Keig PM; Ingham E; Kerr KG Invasion of human type II pneumocytes by Burkholderia cepacia MICROBIAL PATHOGENESIS 30 167-170, 2001
DOI:10.1006/mpat.2000.0418
Fisher J; McEwen HMJ; Barnett PI; Bell CJ; Stewart TD; Stone MH; Ingham E Wear of polyethylene in artificial knee joints CURRENT ORTHOPAEDICS 15 399-405, 2001
DOI:10.1054/cuor.2001.0190
Nevelos JE; Ingham E; Doyle C; Nevelos AB; Fisher J The influence of acetabular cup angle on the wear of "BIOLOX Forte" alumina ceramic bearing couples in a hip joint simulator JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 12 141-144, 2001
DOI:10.1023/A:1008970027306
Saadatzadeh MR; Ashbee HR; Holland KT; Ingham E Production of the mycelial phase of Malassezia in vitro MEDICAL MYCOLOGY 39 487-493, 2001
DOI:10.1080/714031063
Wilcox HE; Farrar MD; Cunliffe WJ; Holland KT; Ingham E Human peripheral blood mononuclear cell response to Propionibacterium acnes heat shock proteins in inflammatory, 2000
Ingham E; Grundy I; Wilcox HE; Farrer M; Cunliffe WJ; Holland KT Antibodies to Propionibacterium acnes HSP 60 and 70 in patients with acne, resolved acne and controls, 2000
Ingham E; Green TR; Stone MH; Kowalski R; Watkins N; Fisher J Production of TNF-alpha and bone resorbing activity by macrophages in response to different types of bone cement particles BIOMATERIALS 21 1005-1013, 2000
DOI:10.1016/S0142-9612(99)00261-6
Matthews JB; Besong AA; Green TR; Stone MH; Wroblewski BM; Fisher J; Ingham E Evaluation of the response of primary human peripheral blood mononuclear phagocytes to challenge with In vitro generated clinically relevant UHMWPE particles of known size and dose JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 52 296-307, 2000
DOI:10.1002/1097-4636(200011)52:2<296::aid-jbm8>3.0.CO;2-9
Matthews JB; Green TR; Stone MH; Wroblewski BM; Fisher J; Ingham E Comparison of the response of primary human peripheral blood mononuclear phagocytes from different donors to challenge with model polyethylene particles of known size and dose BIOMATERIALS 21 2033-2044, 2000
DOI:10.1016/S0142-9612(00)00089-2
Green TR; Fisher J; Matthews JB; Stone MH; Ingham E Effect of size and dose on bone resorption activity of macrophages by in vitro clinically relevant ultra high molecular weight polyethylene particles JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 53 490-497, 2000
DOI:10.1002/1097-4636(200009)53:5<490::aid-jbm7>3.0.CO;2-7
Pickard J; Fisher J; Ingham E; Egan J; Hallett J Investigation into the tribological condition of acetabular tissue after bipolar joint replacement hip surgery PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 214 361-370, 2000
DOI:10.1243/0954411001535408
Nevelos J; Ingham E; Doyle C; Streicher R; Nevelos A; Walter W; Fisher J Microseparation of the centers of alumina-alumina artificial hip joints during simulator testing produces clinically relevant wear rates and patterns JOURNAL OF ARTHROPLASTY 15 793-795, 2000
DOI:10.1054/arth.2000.8100
Bell J; Besong AA; Tipper JL; Ingham E; Wroblewski BM; Stone MH; Fisher J Influence of gelatin and bovine serum lubricants on ultra-high molecular weight polyethylene wear debris generated in in vitro simulations PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 214 513-518, 2000
DOI:10.1243/0954411001535543
Farrar MD; Ingham E; Holland KT Heat shock proteins and inflammatory acne vulgaris: molecular cloning, overexpression and purification of a Propionibacterium acnes GroEL and DnaK homologue FEMS MICROBIOLOGY LETTERS 191 183-186, 2000
DOI:10.1016/S0378-1097(00)00387-6
Mcnie CM; Barton DC; Ingham E; Tipper JL; Fisher J; Stone MH The prediction of polyethylene wear rate and debris morphology produced by microscopic asperities on femoral heads JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 11 163-174, 2000
DOI:10.1023/A:1008979608563
Roy BR; Nevelos AB; Ingham E; Shaw DL; Fisher J Comparison of ceramic on ceramic to ceramic on polyethylene total hip replacement, 2000
Banks RE; Forbes MA; Patel PM; Storr M; Hallam S; Clarke D; Novick D; Ingham E; Bowmer C; Southgate J; Trejdosiewicz LK; Illingworth J; Perren TJ; Selby PJ Subcutaneous administration of recombinant glycosylated interleukin 6 in patients with cancer: Pharmacokinetics, pharmacodynamics and immunomodulatory effects CYTOKINE 12 388-396, 2000
DOI:10.1006/cyto.1999.0556
Jin ZM; Pickard JE; Forster H; Ingham E; Fisher J Frictional behaviour of bovine articular cartilage BIORHEOLOGY 37 57-63, 2000
Nevelos J; Ingham E; Doyle C; Streicher R; Nevelos A; Fisher J Micro-separation in vitro produces clinically relevant wear of ceramic-ceramic total hip replacements, 2000
Ingham E; Fisher J Biological reactions to wear debris in total joint replacement PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 214 21-37, 2000
DOI:10.1243/0954411001535219
Korossis SA; Fisher J; Ingham E Cardiac valve replacement: A bioengineering approach BIO-MEDICAL MATERIALS AND ENGINEERING 10 83-124, 2000
Landers P; Kerr KG; Rowbotham TJ; Tipper JL; Keig PM; Ingham E; Denton M Survival and growth of Burkholderia cepacia within the free-living amoeba Acanthamoeba polyphaga EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY&INFECTIOUS DISEASES 19 121-123, 2000
DOI:10.1007/s100960050442
Kesavan S; Holland KT; Ingham E The effects of lipid extraction on the immunomodulatory activity of Malassezia species in vitro MEDICAL MYCOLOGY 38 239-247, 2000
DOI:10.1080/714030945
Jappe U; Ingham E; Wilcox H; Henwood JA; Holland KT Early stimulation of umbilical cord blood lymphocytes by P. acnes but not tetanus toxoid despite blocking MHC class II HLA-DR, -DP, -DQ suggests T-cell mitogenic activity Archives of Dermatological Research 292 pp.195-, 2000
Russell S; Forsey R; Cruse-Sawyer J; Kearney J; Ingham E Needlepunched non-resorbable matrices for tissue engineering Technical Textiles International 9 13-16, 2000
Matthews JB; Green TR; Stone MH; Wroblewski BM; Fisher J; Ingham E Comparison of the response of primary murine peritoneal macrophages and the U937 human histiocytic cell line to challenge with in vitro generated clinically relevant UHMWPE particles BIO-MEDICAL MATERIALS AND ENGINEERING 10 229-240, 2000
Matthews JB; Besong AA; Green TR; Stone MH; Wroblewski BM; Fisher J; Ingham E Evaluation of the response of primary human peripheral blood mononuclear phagocytes to challenge with in vitro generated clinically relevant UHMWPE particles of known size and dose Journal of Biomedical Materials Research 52 296-307, 2000
Ingham E; Fisher J Biological reactions to wear debris in total joint replacement Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 214 21-37, 2000
Tipper JL; Ingham E; Hailey JL; Besong AA; Fisher J; Wroblewski BM; Stone MH Quantitative analysis of polyethylene wear debris, wear rate and head damage in retrieved Charnley hip prostheses Journal of Materials Science: Materials in Medicine 11 117-124, 2000
Green TR; Fisher J; Bridget Matthews J; Stone MH; Ingham E Effect of size and dose on bone resorption activity of macrophages by in vitro clinically relevant ultra high molecular weight polyethylene particles Journal of Biomedical Materials Research 53 490-497, 2000
Ingham E; Green TR; Stone MH; Kowalski R; Watkins N; Fisher J Production of TNF-α and bone resorbing activity by macrophages in response to different types of bone cement particles Biomaterials 21 1005-1013, 2000
Pickard J; Fisher J; Ingham E; Egan J; Hallctt J Investigation into the tribological condition of acetabular tissue after bipolar joint replacement hip surgery Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 214 361-370, 2000
Nevelos JE; Ingham E; Doyle C; Fisher J; Nevelos AB Analysis of retrieved alumina ceramic components from Mittelmeier total hip prostheses Biomaterials 20 1833-1840, 1999
Endo MM; Barbour PSM; Barton DC; Wroblewski BM; Fisher J; Tipper JL; Ingham E; Stone MH A comparison of the wear and debris generation of GUR 1120 (compression moulded) and GUR 4150HP tram extruded) ultra high molecular weight polyethylene BIO-MEDICAL MATERIALS AND ENGINEERING 9 113-124, 1999
Farrar MD; Ingham E; Holland KT Cloning, sequencing and overexpression of the Propionibacterium acnes dnaK (Heat Shock Protein 70) Homologue Journal of Investigative Dermatology 112 pp.636-, 1999
Kerr KG; Mooney L; Devine MA; Ingham E The effect of sub-inhibitory concentrations of fosfomycin on adherence to T84 and hep2 cells and shigatoxin production by shiga-toxigenic Escherichia coli. Clinical Microbiology and Infection 5 pp.336-, 1999
Farrar M; Ingham E; Holland KT Cloning and overexpression of a Propionibacterium acnes groEL (Heat shock protein 60) homologue and purification, 1999
Banks RE; Forbes MA; Kinsey SE; Stanley A; Ingham E; Walters CE; Selby PJ Release of the angiogenic cytokine vascular endothelial growth factor from platelets - reply to the letter from Vermeulen et al. British Journal of Cancer 79 370-373, 1999
Jappe U; Wilcox HE; Ingham E; Holland KT Is there a mitogen or superantigen produced by propionibacterium acnes?, 1999
Ingham E The immunology of Propionibacterium acnes and acne CURRENT OPINION IN INFECTIOUS DISEASES 12 191-197, 1999
Tipper JL; Ingham E; Hailey JL; Besong AA; Fisher J; Wroblewski BM; Stone MH Quantitative analysis of polyethylene wear debris, wear rate and head damage in retrieved Charnley hip prostheses JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 11 117-124, 1999
Tipper JL; Firkins PJ; Ingham E; Fisher J; Stone MH; Farrar R Quantitative analysis of the wear and wear debris from low and high carbon content cobalt chrome alloys used in metal on metal total hip replacements JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 10 353-362, 1999
DOI:10.1023/A:1026473723777
Besong AA; Tipper JL; Mathews BJ; Ingham E; Stone MH; Fisher J The influence of lubricant on the morphology of ultra-high molecular weight polyethylene wear debris generated in laboratory tests PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 213 155-158, 1999
DOI:10.1243/0954411991534870
Nevelos JE; Ingham E; Doyle C; Fisher J; Nevelos AB Analysis of retrieved alumina ceramic components from Mittelmeier total hip prostheses BIOMATERIALS 20 1833-1840, 1999
DOI:10.1016/S0142-9612(99)00081-2
Wilcox HE; Cunliffe WJ; Holland KT; Ingham E Human peripheral blood mononuclear cell response to Propionibacterium acnes and and heat shock proteins in, 1999
Germain MA; Tipper JL; Ingham E; Makarem R; Wroblewski BM; Fisher J Analysis of debris from brushing the femoral canal with a plastic brush - a potential cause of loosening in total hip replacement PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 213 503-506, 1999
DOI:10.1243/0954411991535112
Besong AA; Tipper JL; Ingham E; Stone MH; Wroblewski BM; Fisher J Quantitative comparison of wear debris from UHMWPE that has and has not been sterilised by gamma irradiation JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 80B 340-344, 1998
DOI:10.1302/0301-620X.80B2.8234
Kesavan S; Walters CE; Holland KT; Ingham E The effects of Malassezia on pro-inflammatory cytokine production by human peripheral blood mononuclear cells in vitro MEDICAL MYCOLOGY 36 97-106, 1998
DOI:10.1046/j.1365-280X.1998.00137.x
Keig P; Ingham E; Denton M; Kerr KG Effect of growth phase on invasion of A549 cells by Burkholderia cepacia. Pediatric Pulmonology 17 pp311-, 1998
Holland KT; Aldana O; Bojar RA; Cunliffe WJ; Eady EA; Holland DB; Ingham E; McGeown C; Till A; Walters C Propionibacterium acnes and acne DERMATOLOGY 196 67-68, 1998
DOI:10.1159/000017870
Banks RE; Forbes MA; Kinsey SE; Stanley A; Ingham E; Walters C; Selby PJ Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology BRITISH JOURNAL OF CANCER 77 956-964, 1998
DOI:10.1038/bjc.1998.158
Banks RE; Forbes MA; Kinsey SE; Stanley A; Ingham E; Walters C; Selby PJ Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: Significance for VEGF measurements and cancer biology British Journal of Cancer 77 956-964, 1998
Walters CE; Richards S; Eady EA; Cove JH; Cunliffe WJ; Ingham E Anti-inflammatory properties of erythromycin in mononuclear cells are not apoptosis-related Journal of Investigative Dermatology 110 pp.644-, 1998
Chan PF; Foster SJ; Ingham E; Clements MO Journal of Bacteriology (Editorship) Applied and Environmental Microbiology 280 pp6082-, 1998
Layton AM; Morris C; Cunliffe WJ; Ingham E Immunohistochemical investigation of evolving inflammation in lesions of acne vulgaris EXPERIMENTAL DERMATOLOGY 7 191-197, 1998
DOI:10.1111/j.1600-0625.1998.tb00323.x
Ingham E; Walters CE; Eady EA; Cove JH; Kearney JN; Cunliffe WJ Inflammation in acne vulgaris: Failure of skin micro-organisms to modulate keratinocyte interleukin 1 alpha production in vitro DERMATOLOGY 196 86-88, 1998
DOI:10.1159/000017877
Banks RE; Forbes MA; Stanley AJ; Ingham E; Walters CE; Selby PJ Presence of vascular endothelial growth factor (VEGF) in megakaryocytes and platelets. British Journal of Cancer 77 956-964, 1998
Chan PF; Foster SJ; Ingham E; Clements MO The Staphylococcus aureus alternative sigma factor sigma(B) controls the environmental stress response but not starvation survival or pathogenicity in a mouse abscess model JOURNAL OF BACTERIOLOGY 180 6082-6089, 1998
Keig P; Ingham E; Denton M; Kerr KG Invasion of human type II pneumocytes by Burkholderia cepacia Pediatric Pulmonology 17 pp311-, 1998
Pickard JE; Fisher J; Ingham E; Egan J Investigation into the effects of proteins and lipids on the frictional properties of articular cartilage BIOMATERIALS 19 1807-1812, 1998
DOI:10.1016/S0142-9612(98)00147-1
Tipper JL; Ingham E; Cove JH; Todd NJ; Kerr KG Survival and multiplication of Burkholderia cepacia within respiratory epithelial cells Clinical Microbiology and Infection 4 450-459, 1998
Pickard J; Ingham E; Egan J; Fisher J Investigation into the effect of proteoglycan molecules on the tribological properties of cartilage joint tissues PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE 212 177-182, 1998
DOI:10.1243/0954411981533953
Minakawa H; Stone MH; Wroblewski BM; Lancaster JG; Ingham E; Fisher J Quantification of third-body damage and its effect on UHMWPE wear with different types of femoral head JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 80B 894-899, 1998
DOI:10.1302/0301-620X.80B5.8675
Green TR; Fisher J; Stone M; Wroblewski BM; Ingham E Polyethylene particles of a 'critical size' are necessary for the induction of cytokines by macrophages in vitro BIOMATERIALS 19 2297-2302, 1998
DOI:10.1016/S0142-9612(98)00140-9
Holland KT; Aldana O; Bojar RA; Cunliffe WJ; Eady EA; Holland DB; Ingham E; McGeown C; Till A; Walters C Propionibacterium acnes and acne Dermatology 196 67-68, 1998
Besong AA; Tipper JL; Ingham E; Stone MH; Wroblewski BM; Fisher J Quantitative comparison of wear debris from UHMWPE that has and has not been sterilised by gamma irradiation Journal of Bone and Joint Surgery - Series B 80 340-344, 1998
Pickard J; Ingham E; Egan J; Fisher J Investigation into the effect of proteoglycan molecules on the tribological properties of cartilage joint tissues Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 212 177-182, 1998
Besong AA; Hailey JL; Ingham E; Stone M; Wroblewski BM; Fisher J A study of the combined effects of shelf ageing following irradiation in air and counterface roughness on the wear of UHMWPE BIO-MEDICAL MATERIALS AND ENGINEERING 7 59-65, 1997
Khammo N; McPhie P; Settle JAD; Ingham E; Kearney JN Effect of burn patient serum on fibroblast and keratinocyte cell morphology Burns 23 212-217, 1997
Daniels JT; Kearney JN; Ingham E An investigation into the potential of extracellular matrix factors for attachment and proliferation of human keratinocytes on skin substitutes Burns 23 26-31, 1997
Holland KT; Aldana O; Bojar RA; Cunliffe WJ; Eady EA; Holland DB; Ingham E; McGeown C; Till A; Walters CE Propionibacterium acnes and acne, 1997
Carter RW; Patel PM; Stanley AJ; Ingham E; Wadhwa M; Bird C; Thorpe R; Selby PJ; Banks RE Production and characterization of monoclonal antibodies to human interleukin-12 HYBRIDOMA 16 363-369, 1997
DOI:10.1089/hyb.1997.16.363
Kesavan S; Walters CE; Holland KT; Ingham E Malassezia species, pro-inflammatory cytokine, blood mononuclearcells, vitro Journal of Medical and Veterinary Mycology. Supplement 36 97-106, 1997
Ketheesan N; Ingham E; Kearney JN; Rasaretnam R Donor valves as substitutes for heart valve replacement. The Ceylon medical journal 42 85-90, 1997
Ashbee HR; Muir SR; Cunliffe WJ; Ingham E IgG subclasses specific to Staphylococcus epidermidis and Propionibacterium acnes in patients with acne vulgaris BRITISH JOURNAL OF DERMATOLOGY 136 730-733, 1997
DOI:10.1111/j.1365-2133.1997.tb03660.x
Wilcox HE; Ashbee HR; Cunliffe WJ; Ingham E Characterisation of the human peripheral blood T-cell response to P-acnes, 1997
Kesavan S; Holland KT; Cunliffe WJ; Ingham E Reduction of pro-inflammatory cytokines in response to viable Malassezia species is interleukin-10 independent. Journal of Investigative Dermatology 109 pp.449-, 1997
Kesavan S; Holland KT; Cunliffe WJ; Ingham E The effects of de-lipidisation of the immunomodulatory activity of Malassezia species Journal of Investigative Dermatology 108 pp.389-, 1997
Walters CE; Richards S; Eady EA; Cove JH; Cunliffe WJ; Ingham E Anti-inflammatory properties of erythromycin: Modulation of lymphocyte HLA-DR and interleukin-2 receptor expression in vitro, 1997
Besong A; Hailey JL; Ingham E; Stone MH; Wroblewski B; Fisher J A study of the combined effects of shelf ageing following irradiation in air and counterface roughness on the wear of Biomaterials 7 56-65, 1997
Carter RW; Patel PM; Stanley AJ; Ingham E; Wadhwa M; Bird C; Thorpe R; Selby PJ; Banks RE Production and characterization of monoclonal antibodies to human interleukin-12 Hybridoma 16 363-369, 1997
McGeown CH; Holland DB; Ingham E; Cunliffe WJ Inflammatory events in post-adolescent acne, 1997
Walters CE; Richards S; Eady EA; Cove JH; Cunliffe WJ; Ingham E Anti-inflammatory properties of erythromycin in mononuclear cells are not apoptosis-related, 1997
Walters CE; Richards S; Eady EA; Cove JH; Cunliffe WJ; Ingham E Anti-inflammatory effects of erythromycin on mononuclear cell adhesion molecule expression in vitro, 1997
McGeown CH; Goulden V; Holland DB; Ingham E; Cunliffe WJ Sebum excretion rate in post-adolescent acne compared to controls and adolescent acne, 1997
Fisher J; Barbour PSM; King MJ; Besong AA; Hailey J; Tipper JL; Ingham E; Stone M; Wroblewski BM Wear of ultrahigh molecular weight polyethylene in artificial joints: A new approach to the quantification of wear debris, 1997
Khammo N; McPhie P; Settle J; Dezulski P; Ingham E; Kearney JN The effect of burn patient serum on the morphology of human keratinocytes and fibroblasts in vitro. Burns 23 212-217, 1997
Ingham E; Walters CE; Eady EA; Cove JH; Kearney JN; Cunliffe WJ Inflammation in acne vulgaris - Failure of skin micro organisms to modulate keratinocyte IL-1 alpha production in, 1997
Daniels J; Kearney JN; Ingham E An investigation into the potential of extracellular matrix factors for attachment and proliferation of human keratinocytes on skin substitutes.An investigation into the potential of extracellular matrix factors for attachment and proliferation of human k Burns 23 26-31, 1997
Fruin AM; Ashbee HR; Holland KT; Cunliffe WJ; Ingham E T-lymphocyte responses to heat shock protein 70 in patients with acne vulgaris and normal controls. Journal of Investigative Dermatology 107 pp.487-, 1996
Ketheesan N; Kearney JN; Ingham E Assessment of the immunogenicity and viability of human homologous cardiac valves. The Journal of Heart Valve Disease 5 144-147, 1996
Kesavan S; Walters CE; Holland KT; Cunliffe WJ; Ingham E Malassezia furfur suppresses the release of interleukin- beta (IL-beta), interleukin-1beta (IL-1beta and tumour necrosis factor-alpha (TBF-alpha) from human peripheral blood mononuclear phagocytes in vitro. Journal of Investigative Dermatology 107 pp.452-, 1996
Adams DJ; Escott GM; Ingham E; Walters CE Expression of chitinase activity during monocyte differentiation In Chitin Enzymology , 1996
Walters CE; Richards S; Eady EA; Cove JH; Ingham E Novel anti-inflammatory roperties of erythromycin: In vitro reduction of monocyte intercellular adhesion molecule-I expression, 1996
Kendall RG; Ingham E; Norfolk DR Interleukins 3 and 4 stimulate erythropoietin production by a hepatoma derived cell line, 1996
Banks RE; Forbes MA; Stanley A; Kinsey SE; Ingham E; Walters SJ; Selby PJ Presence of vascular endothelial growth factor (VEGF) in megakaryocytes and platelets, 1996
Ketheesan N; Kearney JN; Ingham E The effect of cryopreservation on the immunogenicity of allogeneic cardiac valves CRYOBIOLOGY 33 41-53, 1996
DOI:10.1006/cryo.1996.0005
Kesavan S; Ingham E; Holland KT; Cunliffe WJ Down-regulation of pro-inflammatory tumour necrosis factor-alpha, interleukin-6 and interleukin-1 beta by, 1996
Stanley AJ; Carter RW; Ingham E; Patel PM; Banks RE; Selby PJ Detection of the p35 and p40 subunits of interleukin-12 in melanoma and bladder cancer cell lines INERLEUKIN 12: CELLULAR AND MOLECULAR IMMUNOLOGY OF AN IMPORTANT REGULATORY CYTOKINE 795 384-386, 1996
DOI:10.1111/j.1749-6632.1996.tb52700.x
Daniels J; Kearney JN; Ingham E Human keratinocyte isolation and cell culture: a survey of current practices in the UK Burns 22 35-39, 1996
Khammo N; Ingham E; Dziewulski P; Settle J; Mcphie P; Kearney JN Effect of burn patient serum on fibroblast and keratinocyte morphology, 1996
Hailey JL; Ingham E; Stone M; Wroblewski BM Ultra-high molecular weight polyethylene wear debris generated in vivo and in laboratory tests; the influence of counterface roughness Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 210 3-10, 1996
Ketheesan N; Kearney JN; Ingham E Assessment of immunogenicity and viability of homologous human cardiac valves in vitro JOURNAL OF HEART VALVE DISEASE 5 144-147, 1996
Hailey JL; Ingham E; Wroblewski BM; Stone M; Fisher J Morphology of ultra-high molecular weight polyethylene wear debris isolated from a series of Charnley hip arthroplasties Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium 2 550-550, 1996
Harris IR; Yee KC; Walters CE; Cunliffe WJ; Kearney JN; Wood EJ; Ingham E Cytokine and protease levels in healing and non-healing chronic venous leg ulcers Experimental Dermatology 4 342-349, 1995
Daniels J; Harris IR; Ingham E; Kearney JN Calcium: a crucial consideration in serum-free keratinocyte culture medium. Experimental Dermatology 4 183-191, 1995
WALTERS C; INGHAM E; EADY E; COVE J; KEARNEY J; CUNLIFFE W IN-VITRO MODULATION OF KERATINOCYTE-DERIVED INTERLEUKIN-1-ALPHA (IL-1-ALPHA) AND PERIPHERAL-BLOOD MONONUCLEAR CELL-DERIVED IL-1-BETA RELEASE IN RESPONSE TO CUTANEOUS COMMENSAL MICROORGANISMS INFECTION AND IMMUNITY 63 1223-1228, 1995
Harris IR; Yee KC; Walters CE; Kearney JN; Cunliffe WJ; Wood EJ; Ingham E Cytokine and protease levels in healing and non healing chronic venous leg ulcers. Experimental Dermatology 4 192-198, 1995
Ingham E In vitro modulation of keratinocyte-derived IL-1 alpha and peripheral blood mononyclear cell-derived IL-1 beta release in response to cutaneous commensal microorganisms. Infection and Immunity 63, 1223-1228, 1995
Hailey JL; Ingham E; Fisher J; Dowson D; Wroblewski B The influence of tribological conditions on the morphology of polyethylene wear debris, 1994
KETHEESAN N; INGHAM E; GOWLAND G; KEARNEY J IN-VITRO IMMUNOGENICITY OF ALLOGENEIC CARDIAC VALVES EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY 8 549-553, 1994
DOI:10.1016/1010-7940(94)90074-4
KENDALL R; INGHAM E; NORFOLK D THE EFFECT OF CYTOKINES ON THE IN-VITRO ERYTHROPOIETIN BIOASSAY CLINICAL AND LABORATORY HAEMATOLOGY 16 273-279, 1994
Ashbee HR; Fruin A; Holland KT; Cunliffe WJ; Ingham E Humoral immunity to Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrheic dermatitis and controls Experimental Dermatology 3 227-233, 1994
Ashbee HR; Ingham E; Holland KT; Cunliffe WJ Cell-mediated immune responses to Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrheic dermatitis and controls Experimental Dermatology 3 106-112, 1994
Eady EA; Ingham E Propionibacterium acnes - Friend or foe? Reviews in Medical Microbiology 5 163-173, 1994
Ashbee HR; Ingham E; Holland KT; Cunliffe WJ The carriage of Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrhoeic dermatitis and controls. Br J Dermatol 129 533-540, 1993
INGHAM E; MATTHEWS J; KEARNEY J; GOWLAND G THE EFFECTS OF VARIATION OF CRYOPRESERVATION PROTOCOLS ON THE IMMUNOGENICITY OF ALLOGENEIC SKIN-GRAFTS CRYOBIOLOGY 30 443-458, 1993
DOI:10.1006/cryo.1993.1045
EADY E; INGHAM E; WALTERS C; COVE J; CUNLIFFE W MODULATION OF COMEDONAL LEVELS OF INTERLEUKIN-1 IN ACNE PATIENTS TREATED WITH TETRACYCLINES JOURNAL OF INVESTIGATIVE DERMATOLOGY 101 86-91, 1993
DOI:10.1111/1523-1747.ep12360123
ASHBEE H; INGHAM E; HOLLAND K; CUNLIFFE W THE CARRIAGE OF MALASSEZIA-FURFUR SEROVARS-A, SEROVARS-B AND SEROVARS C IN PATIENTS WITH PITYRIASIS-VERSICOLOR, SEBORRHEIC DERMATITIS AND CONTROLS BRITISH JOURNAL OF DERMATOLOGY 129 533-540, 1993
DOI:10.1111/j.1365-2133.1993.tb00480.x
Ingham E Modulation of comedonal IL-1 levels in acne patients treated with minocycline and tetracycline. Journal of Investigative Dermatology 101, 86-91, 1993
CUNNINGHAM A; INGHAM E; GOWLAND G HUMORAL RESPONSES TO MALASSEZIA-FURFUR SEROVARS A, B AND C IN NORMAL INDIVIDUALS OF VARIOUS AGES BRITISH JOURNAL OF DERMATOLOGY 127 476-481, 1992
DOI:10.1111/j.1365-2133.1992.tb14843.x
INGHAM E; EADY E; GOODWIN C; COVE J; CUNLIFFE W PRO-INFLAMMATORY LEVELS OF INTERLEUKIN-1-ALPHA-LIKE BIOACTIVITY ARE PRESENT IN THE MAJORITY OF OPEN COMEDONES IN ACNE-VULGARIS JOURNAL OF INVESTIGATIVE DERMATOLOGY 98 895-901, 1992
DOI:10.1111/1523-1747.ep12460324
Ingham E Effect of variation of the cryopreservation protocol on the immunogenicity of allogeneic murine skin. Cryobiology 30, 443-458, 1992
Ingham E Pro-inflammatory levels of interleukin-1 alpha like bioactivity are present in the majority of comedones in acne vulgaris. Journal of Investigative Dermatology 98, 895-901, 1992
INGHAM E; TURNBULL L; KEARNEY J THE EFFECTS OF MINOCYCLINE AND TETRACYCLINE ON THE MITOTIC RESPONSE OF HUMAN PERIPHERAL-BLOOD LYMPHOCYTES JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 27 607-617, 1991
DOI:10.1093/jac/27.5.607
INGHAM E THE EFFECTS OF TETRACYCLINES AND ERYTHROMYCIN ON COMPLEMENT ACTIVATION INVITRO ACTA DERMATO-VENEREOLOGICA 70 531-534, 1990
INGHAM E MODULATION OF THE PROLIFERATIVE RESPONSE OF MURINE THYMOCYTES STIMULATED BY IL-1, AND ENHANCEMENT OF IL-1-BETA SECRETION FROM MONONUCLEAR PHAGOCYTES BY TETRACYCLINES JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY 26 61-70, 1990
DOI:10.1093/jac/26.1.61
Whicher J; Ingham E Cytokine measurements in body fluids. European cytokine network 1 239-243, 1990
CUNNINGHAM A; LEEMING J; INGHAM E; GOWLAND G DIFFERENTIATION OF 3 SEROVARS OF MALASSEZIA-FURFUR JOURNAL OF APPLIED BACTERIOLOGY 68 439-446, 1990
DOI:10.1111/j.1365-2672.1990.tb02894.x
KEETHEESAN N; INGHAM E; GOWLAND G ANTIBIOTICS AND HUMAN LYMPHOCYTE-ACTIVATING FACTOR (LAF) PRODUCTION THEORETICAL SURGERY 5 177-179, 1990
LEEMING J; INGHAM E; CUNLIFFE W THE MICROBIAL CONTENT AND COMPLEMENT C-3 CLEAVING CAPACITY OF COMEDONES IN ACNE-VULGARIS ACTA DERMATO-VENEREOLOGICA 68 468-473, 1988
INGHAM E; GOWLAND G; WARD R; HOLLAND K; CUNLIFFE W ANTIBODIES TO P-ACNES AND P-ACNES EXOCELLULAR ENZYMES IN THE NORMAL POPULATION AT VARIOUS AGES AND IN PATIENTS WITH ACNE-VULGARIS BRITISH JOURNAL OF DERMATOLOGY 116 805-812, 1987
DOI:10.1111/j.1365-2133.1987.tb04899.x
HOLLAND D; INGHAM E; GOWLAND G; CUNLIFFE W IGG SUBCLASSES IN ACNE-VULGARIS BRITISH JOURNAL OF DERMATOLOGY 114 349-351, 1986
DOI:10.1111/j.1365-2133.1986.tb02826.x
HOLLAND K; INGHAM E; EADY E; GOWLAND G TOXIC SHOCK SYNDROME - THE EFFECT OF SOLID-PHASE MATERIALS ON THE PHYSIOLOGY OF STAPHYLOCOCCUS-AUREUS POSTGRADUATE MEDICAL JOURNAL 61 39-43, 1985
INGHAM E; EADY E; HOLLAND K; GOWLAND G EFFECTS OF TAMPON MATERIALS ON THE INVITRO PHYSIOLOGY OF A TOXIC SHOCK SYNDROME STRAIN OF STAPHYLOCOCCUS-AUREUS JOURNAL OF MEDICAL MICROBIOLOGY 20 87-95, 1985
INGHAM E; GOWLAND G; TAYLOR K STABILIZATION OF C-3 IN EDTA-PLASMA AT PH 6.0 MEDICAL LABORATORY SCIENCES 42 30-34, 1985
HOLLAND K; DAVIS W; INGHAM E; GOWLAND G A COMPARISON OF THE INVITRO ANTIBACTERIAL AND COMPLEMENT ACTIVATING EFFECT OF OPSITE AND TEGADERM DRESSINGS JOURNAL OF HOSPITAL INFECTION 5 323-328, 1984
DOI:10.1016/0195-6701(84)90082-3
KEARNEY J; INGHAM E; CUNLIFFE W; HOLLAND K CORRELATIONS BETWEEN HUMAN-SKIN BACTERIA AND SKIN LIPIDS BRITISH JOURNAL OF DERMATOLOGY 110 593-599, 1984
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W P-ACNES EXOCELLULAR ENZYMES FAIL TO CLEAVE COMPLEMENT PROTEINS INVITRO JOURNAL OF INVESTIGATIVE DERMATOLOGY 82 546-547, 1984
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W DIFFICULTIES IN PRODUCING ANTIBODIES TO PURIFIED PROPIONIBACTERIUM-ACNES EXOCELLULAR ENZYMES BRITISH JOURNAL OF DERMATOLOGY 110 61-66, 1984
DOI:10.1111/j.1365-2133.1984.tb07313.x
INGHAM E; GOWLAND G COMPLEMENT, HISTAMINE-RELEASE, AND TREATMENT OF UPPER-RESPIRATORY-TRACT INFECTIONS LANCET 2 1027-1027, 1983
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W DIFFICULTIES IN PRODUCING ANTIBODIES TO PURIFIED P-ACNES EXOCELLULAR ENZYMES JOURNAL OF INVESTIGATIVE DERMATOLOGY 80 376-376, 1983
EADY E; INGHAM E; HOLLAND K; GOWLAND G INTERACTIONS OF TAMPON FIBERS WITH GROWTH OF STAPHYLOCOCCUS-AUREUS INVITRO LANCET 1 818-818, 1983
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W STUDIES OF THE EXOCELLULAR PROTEOLYTIC ACTIVITY PRODUCED BY PROPIONIBACTERIUM-ACNES JOURNAL OF INVESTIGATIVE DERMATOLOGY 78 328-329, 1982
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W PARTIAL-PURIFICATION AND CHARACTERIZATION OF LIPASE (EC 3.1.1.3) FROM PROPIONIBACTERIUM-ACNES JOURNAL OF GENERAL MICROBIOLOGY 124 393-401, 1981
Holland KT; Ingham E; Cunliffe WJ A review. The microbiology of acne Journal of Applied Bacteriology 51 195-215, 1981
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W PURIFICATION AND PARTIAL CHARACTERIZATION OF AN ACID-PHOSPHATASE (EC 3.1.3.2) PRODUCED BY PROPIONIBACTERIUM-ACNES JOURNAL OF GENERAL MICROBIOLOGY 118 59-65, 1980
INGHAM E; HOLLAND K; GOWLAND G; CUNLIFFE W PURIFICATION AND PARTIAL CHARACTERIZATION OF HYALURONATE LYASE (EC-42 2 1) FROM PROPIONIBACTERIUM-ACNES JOURNAL OF GENERAL MICROBIOLOGY 115 411-418, 1979
